EGFR Inhibitors

Cat. No. Product Name / Activity
5318 AEE 788
Potent EGFR and VEGFR inhibitor
6812 Afatinib dimaleate
Potent dual specificity EGFR/HER2 inhibitor; active in vivo
1276 AG 1478 hydrochloride
Highly potent EGFR-kinase inhibitor
0414 AG 490
EGFR-kinase inhibitor. Also JAK2, JAK3 inhibitor
1555 AG 825
Selective ErbB2 inhibitor
2417 BIBU 1361 dihydrochloride
Selective inhibitor of EGFR-kinase
2416 BIBX 1382 dihydrochloride
Highly selective EGFR-kinase inhibitor
5022 BMS 599626 dihydrochloride
Potent, selective EGFR and ErbB2 inhibitor
5916 Canertinib dihydrochloride
Potent EGFR kinase inhibitor
3360 CGP 52411
EGFR inhibitor. Also inhibits Aβ42 fibril formation
6231 Dacomitinib
Potent irreversible pan ErbB inhibitor
4502 DIM
Inhibits EGFR activation; also induces apoptosis
7194 Erlotinib Hydrochloride
Potent, reversible EGFR tyrosine kinase inhibitor
1110 Genistein
EGFR kinase inhibitor. Also estrogen and PPARγ ligand
2239 GW 583340 dihydrochloride
Potent dual EGFR/ErbB2 inhibitor; orally active
3580 HKI 357
Dual irreversible inhibitor of ErbB2 and EGFR
3000 Iressa
Orally active, selective EGFR inhibitor
6962 JBJ-03-142-02
Highly potent EGFR and ErbB2 inhibitor; inhibts wild type and mutated receptors
3352 JNJ 28871063 hydrochloride
Potent ErbB receptor family inhibitor
6811 Lapatinib
Potent and selective dual ErbB2 (HER-2) and EGFR inhibitor
1331 Lavendustin A
EGFR, p60c-src inhibitor
7371 Neratinib
Potent HER2 receptor tyrosine kinase and EGFR kinase inhibitor
1037 PD 153035 hydrochloride
EGFR-kinase inhibitor
2615 PD 158780
Potent ErbB receptor family inhibitor
6349 Pelitinib
Potent and irreversible EGFR inhibitor; orally bioavailable
4941 PKI 166 hydrochloride
Potent EGFR-kinase inhibitor
2794 PP 3
EGFR-kinase inhibitor. Also Src kinase negative control
3599 TAK 165
Potent and selective ErbB2 inhibitor
3115 WHI-P 154
Potent EGFR inhibitor. Also inhibits JAK3