Hypoxia Inducible Factor (HIF) Inhibitors

Cat. No. Product Name / Activity
5953 Adaptaquin
HIF-prolyl hydroxylase-2 (PHD2) inhibitor; antioxidant
5582 TAT-cyclo-CLLFVY
Selective HIF-1 dimerization inhibitor
4408 DMOG
Inhibitor of hypoxia-inducible factor α (HIF-α) prolyl hydroxylase (HIF-PH)
5520 Echinomycin
Highly potent and selective HIF-1α inhibitor
6653 FM19G11
HIF α-subunit inhibitor
5655 GN 44028
Potent HIF-1α inhibitor
4451 IOX 2
Potent, selective HIF-1α prolyl hydroxylase-2 (PHD2) inhibitor
4324 KC7F2
HIF-1α inhibitor; down-regulates HIF-1α protein synthesis
6322 LW 6
HIF-1α inhibitor; inhibits cellular accumulation of HIF-1α; also malate dehydrogenase-2 inhibitor
2954 PX 12
Thioredoxin-1 inhibitor; attenuates expression of HIF-1α
5243 TC-S 7009
High affinity and selective HIF-2α inhibitor
7774 VH 032
Inhibitor of VHL; blocks interaction of VHL and HIF-α
6156 VH 298
High-affinity inhibitor of VHL; blocks interaction of VHL and HIF-α

Related Targets