Peroxisome proliferator-activated receptor alpha (PPARα) is a member of the nuclear receptor family of ligand-activated transcription factors that heterodimerize with the retinoic X receptor (RXR) to regulate gene expression.
PPARα Agonists |
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Cat. No. | Product Name / Activity |
4190 | CP 775146 |
Selective, high affinity PPARα agonist | |
4113 | Fenofibrate |
PPARα agonist | |
1677 | GW 7647 |
Highly selective, potent PPARα agonist. Orally active | |
1484 | Oleylethanolamide |
PPARα agonist; also GPR55 agonist | |
0879 | Palmitoylethanolamide |
Endogenous lipid with PPARα agonist activity | |
1312 | WY 14643 |
Selective PPARα agonist | |
PPARα Antagonists |
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Cat. No. | Product Name / Activity |
4618 | GW 6471 |
PPARα antagonist | |
1311 | MK 886 |
PPARα antagonist. Also FLAP inhibitor |
Peroxisome proliferator-activated receptor alpha (PPARα) is a member of the nuclear receptor family of ligand-activated transcription factors that heterodimerize with the retinoic X receptor (RXR) to regulate gene expression. PPARα is located primarily in the liver, adipose tissue, kidney, heart, skeletal muscle and large intestine where it is thought to regulate fatty acid synthesis and oxidation, gluconeogenesis, ketogenesis and lipoprotein assembly. The human gene encoding PPARα has been localized to chromosome 22 (22q12-13.1).
Tocris offers the following scientific literature for PPARα to showcase our products. We invite you to request* your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.