PPARδ
Peroxisome proliferator-activated receptor delta (PPARδ), also known as PPARβ, is a member of the nuclear receptor family of ligand-activated transcription factors that heterodimerize with the retinoic X receptor (RXR) to regulate gene expression.
PPARδ Agonists |
|
|---|---|
| Cat. No. | Product Name / Activity |
| 2229 | GW 0742 |
| Highly selective, potent PPARδ agonist | |
| 5674 | GW 501516 |
| Potent and selective PPARδ agonist | |
| 1856 | L-165,041 |
| Potent PPARδ agonist | |
PPARδ Antagonists |
|
| Cat. No. | Product Name / Activity |
| 4344 | FH 535 |
| PPARγ/δ antagonist; also inhibits Wnt/β-catenin signaling | |
| 3433 | GSK 0660 |
| Selective PPARδ antagonist | |
| 3961 | GSK 3787 |
| Potent and selective PPARδ antagonist | |
Peroxisome proliferator-activated receptor delta (PPARδ), also known as PPARβ, is a member of the nuclear receptor family of ligand-activated transcription factors that heterodimerize with the retinoic X receptor (RXR) to regulate gene expression.
PPARδ displays a ubiquitous expression pattern and is thought to regulate placental and gut development, fatty acid oxidation, adaptive thermogenesis, control of cell proliferation and differentiation and tissue repair. The human gene encoding PPARδ has been localized to chromosome 6 (6p21.2).
External sources of pharmacological information for PPARδ :
Literature for PPARδ
Tocris offers the following scientific literature for PPARδ to showcase our products. We invite you to request* your copy today!
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