Glutamate (Metabotropic) Group III Receptor Modulators

Cat. No. Product Name / Activity
5715 (±)-ADX 71743
Negative allosteric modulator of mGlu7 receptors; brain penetrant
4832 AZ 12216052
Positive allosteric modulator of mGlu8 receptors
2963 MMPIP hydrochloride
Potent and selective negative allosteric modulator of mGlu7 receptors
1212 MPEP hydrochloride
Positive allosteric modulator of mGlu4 receptors; also potent mGlu5 antagonist
1214 SIB 1893
Positive allosteric modulator of mGlu4 receptors; also mGlu5 antagonist
4370 TC-N 22A
Potent and selective positive allosteric modulator of mGlu4 receptors
4259 TCN 238
Positive allosteric modulator of mGlu4 receptors
3248 VU 0155041
Potent positive allosteric modulator of mGlu4 receptors
3311 VU 0155041 sodium salt
Potent positive allosteric modulator of mGlu4 receptors; sodium salt of VU 0155041 (Cat. No. 3248)
3707 VU 0361737
Selective positive allosteric modulator of mGlu4 receptors
4371 VU 0364439
Positive allosteric modulator of mGlu4 receptors
4469 VU 0364770
Positive allosteric modulator of mGlu4 receptors
5378 VU 0422288
Selective positive allosteric modulator of group III mGlu receptors
6893 VU 6005649
Positive allosteric modulators of mGlu7 and mGlu8 receptors; also NK1 antagonist; brain penetrant