Melanocortin (MC) Receptor Peptides

Agonists

Cat No Product Name / Activity
3492 ACTH (1-39)
Potent endogenous MC2 agonist
2566 Melanotan II
High affinity melanocortin receptor agonist
3424 γ1-MSH
Selective MC3 receptor agonist
4272 [D-Trp8]-γ-MSH
Selective MC3 receptor agonist
3013 [Nle4,D-Phe7]-α-MSH
Melanocortin receptor agonist
2584 α-MSH
Endogenous melanocortin receptor agonist
5094 PG 931
Potent and selective MC4 receptor agonist

Antagonists

Cat No Product Name / Activity
1831 HS 014
Selective MC4 receptor antagonist
1832 HS 024
Highly potent MC4 receptor antagonist
3426 JKC 363
Potent and selective MC4 receptor antagonist
3438 MCL 0020
Selective MC4 receptor antagonist
5954 MSG 606
Potent human MC1 receptor antagonist; also MC3 and MC5 partial agonist
4919 PG 106
Selective MC3 receptor antagonist

Other

Cat No Product Name / Activity
3611 Lys-γ3-MSH
Pro-opiomelanocortin (POMC) derived peptide
1929 Melanocyte-stimulating hormone release inhibiting factor
Inhibitor of α-MSH release; inhibits opioid effects in vivo
3420 SHU 9119
MC3 and MC4 antagonist; MC5 partial agonist