Ion indicators are small molecules that are used to detect changes in ionic gradients in cells. The detection of metal ions often involves chelation, where the indicator forms a complex with the target metal ion, leading to a chemical or physical change in the indicator that can be analysed with spectroscopic or electrochemical techniques.
Cat. No. | Product Name / Activity |
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7444 | DA ZP1 New |
Fluorogenic Zn(II) sensor for isolation of stem cell derived β cells | |
6255 | Fluo-4 AM |
Cell-permeable, fluorescent Ca2+ indicator | |
2220 | FURA-2AM |
Fluorescent Ca2+ indicator | |
6704 | Indo 1AM |
Fluorescent Ca2+ indicator | |
7870 | ING-2 AM New |
Fluorescent sodium ion (Na+) indicator, membrane permeable | |
7871 | IPG-4 AM New |
Fluorescent potassium ion (K+) indicator, membrane permeable | |
7855 | Mag-Fura-2 AM New |
Magnesium (Mg2+) indicator, membrane permeable | |
7856 | MQAE New |
Fluorescent Cl- indicator; membrane permeable | |
6256 | OG 488 BAPTA-1 AM |
Cell-permeable, fluorescent Ca2+ indicator | |
7873 | Phen Green SK diacetate New |
Heavy metal ion indicator, membrane permeable |
Fluorescent ion indicators provide valuable insights into the effects of drug compounds on cell ion gradients and are compatible with high throughput screening assays. They can be used to identify novel compounds that modulate ion channel activity, understand drug mechanisms of action, and monitor ion dynamics with high sensitivity and selectivity.
Tocris offers the following scientific literature for Fluorescent Ion Indicators to showcase our products. We invite you to request* your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.
This product guide provides a background to the use of Fluorescent Dyes and Probes, as well as a comprehensive list of our: