I3 Receptors

Imidazoline 3 receptors (I3) are members of the imidazoline receptor family, which also include I1 (labeled by clonidine) and I2 (labeled by idazoxan). I3 receptors are located in the pancreatic β-cells and are able to stimulate insulin secretion in a glucose-dependent manner.

Products
Background
Literature

Antagonists

Cat No Product Name / Activity
1131 KU14R
Antagonist of pancreatic imidazoline receptor

Other

Cat No Product Name / Activity
0842 Agmatine sulfate
Putative endogenous imidazoline ligand

Imidazoline 3 receptors (I3) are members of the imidazoline family of receptors, which also include I1 (labeled by clonidine) and I2 (labeled by idazoxan). I3 receptors are located in the pancreatic β-cells and are able to stimulate insulin secretion in a glucose-dependent manner. This is accompanied by inhibition of ATP-sensitive K+ channels.

Little is known about the transduction mechanism of I3 receptors and the gene encoding it has not yet been characterized.

Literature for I3 Receptors

Tocris offers the following scientific literature for I3 Receptors to showcase our products. We invite you to request* or download your copy today!

*Please note that Tocris will only send literature to established scientific business / institute addresses.


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New Product Guide (Spring/Summer 2018)

Our new product guide highlights over 200 new products added to the Tocris Bioscience range during the second half of 2017.

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