I3 Receptors
Imidazoline 3 receptors (I3) are members of the imidazoline receptor family, which also include I1 (labeled by clonidine) and I2 (labeled by idazoxan). I3 receptors are located in the pancreatic β-cells and are able to stimulate insulin secretion in a glucose-dependent manner.
Antagonists |
|
|---|---|
| Cat No | Product Name / Activity |
| 1131 | KU14R |
| Antagonist of pancreatic imidazoline receptor | |
Other |
|
| Cat No | Product Name / Activity |
| 0842 | Agmatine sulfate |
| Putative endogenous imidazoline ligand | |
Imidazoline 3 receptors (I3) are members of the imidazoline family of receptors, which also include I1 (labeled by clonidine) and I2 (labeled by idazoxan). I3 receptors are located in the pancreatic β-cells and are able to stimulate insulin secretion in a glucose-dependent manner. This is accompanied by inhibition of ATP-sensitive K+ channels.
Little is known about the transduction mechanism of I3 receptors and the gene encoding it has not yet been characterized.
Literature for I3 Receptors
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