CCK1 Receptors

The cholecystokinin1 receptor (CCK1 receptor, CCK-A receptor) is a member of the cholecystokinin receptor group of G-protein-coupled receptors that also includes CCK2. CCK1 receptors play a role in food intake, pancreatic exocrine secretion, gall bladder contractility and GI motility.

Products
Background
Gene Data

Agonists

Cat No Product Name / Activity
2411 A-71623
Potent and selective CCK1 agonist; suppresses feeding

Antagonists

Cat No Product Name / Activity
2304 Devazepide
Selective, orally active CCK1 receptor antagonist
2190 SR 27897
Potent and selective CCK1 antagonist

The cholecystokinin1 receptor (CCK1 receptor, CCK-A receptor) is a member of the cholecystokinin receptor group of G-protein-coupled receptors that also includes CCK2. They are located primarily in the pancreas, gall bladder, intestine and vagus nerve where they play a role in food intake, pancreatic exocrine secretion, gall bladder contractility and GI motility. The human CCK1 receptor gene has been localized to chromosome 4 (4p15.1-p15.2).

External sources of pharmacological information for CCK1 Receptors :

CCK1 Receptor Gene Data

Species Gene Symbol Gene Accession No. Protein Accession No.
Human CCKAR NM_000730 P32238
Mouse Cckar NM_009827 O08786
Rat Cckar NM_012688 P30551