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Retinal Stem Cells are formed during embryonic development of the eye in the optic vesicle, where generate the neurons and Müller glia that form part of the mature retina. A small group of retinal stem cells remain at the edge of retina throughout life.
|Cat. No.||Product Name / Activity|
|5329||CKI 7 dihydrochloride|
|CK1 inhibitor; induces retinal cell differentiation from human ESCs and iPSCs|
|Synthetic retinoid; induces differentiation of stem cells|
|Synthetic retinoid; induces neural differentiation of hESCs|
|Endogenous agonist for retinoic acid receptors; inducer of neuronal differentiation|
Tocris offers the following scientific literature for Retinal Stem Cells to showcase our products. We invite you to request* or download your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.
Written by Kirsty E. Clarke, Victoria B. Christie, Andy Whiting and Stefan A. Przyborski, this review provides an overview of the use of small molecules in the control of stem cell growth and differentiation. Key signaling pathways are highlighted, and the regulation of ES cell self-renewal and somatic cell reprogramming is discussed. Compounds available from Tocris are listed.
Stem cells have potential as a source of cells and tissues for research and treatment of disease. This poster summarizes some key protocols demonstrating the use of small molecules across the stem cell workflow, from reprogramming, through self-renewal, storage and differentiation to verification. Advantages of using small molecules are also highlighted.