Hydrocortisone

Pricing Availability Delivery Time Qty
Cat.No. 4093 - Hydrocortisone | C21H30O5 | CAS No. 50-23-7
Description: Adrenal glucocorticoid; immunosuppressant
Chemical Name: 11β,17α,21-Trihydroxypregn-4-ene-3,20-dione
Purity: ≥98% (HPLC)
Datasheet
Citations
Literature

Biological Activity

Adrenal glucocorticoid released in the stress response. Increases glucose production by gluconeogenesis. Immunosuppressant and antidiuretic hormone.

Compound Libraries

Hydrocortisone is also offered as part of the Tocriscreen Plus and Tocriscreen Library of FDA-Approved Compounds. Find out more about compound libraries available from Tocris.

Technical Data

M. Wt 362.46
Formula C21H30O5
Storage Store at RT
Purity ≥98% (HPLC)
CAS Number 50-23-7
PubChem ID 5754
InChI Key JYGXADMDTFJGBT-VWUMJDOOSA-N
Smiles O=C1CC[C@@]2(C)C(CC[C@]3([H])[C@@]([H])2[C@@H](O)C[C@@]4(C)[C@]([H])3CC[C@@](O)4[C@@](CO)=O)=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Solubility Data

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 36.25 100
ethanol 9.06 25

Preparing Stock Solutions

The following data is based on the product molecular weight 362.46. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.76 mL 13.79 mL 27.59 mL
5 mM 0.55 mL 2.76 mL 5.52 mL
10 mM 0.28 mL 1.38 mL 2.76 mL
50 mM 0.06 mL 0.28 mL 0.55 mL

Molarity Calculator

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Reconstitution Calculator

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Dilution Calculator

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Product Datasheets

Certificate of Analysis / Product Datasheet
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Safety Datasheet

References

References are publications that support the products' biological activity.

Khani and Tayek (2001) Cortisol increases gluconeogenesis in humans; its role in the metabolic syndrome. Clin.Sci.(Lond) 101 739 PMID: 11724664


If you know of a relevant reference for Hydrocortisone, please let us know.

View Related Products by Target

Keywords: Hydrocortisone, supplier, glucocorticoids, antiinflammatory, stress, induces, inducers, gluconeogenesis, adrenal, gland, 11b,17a,21-Trihydroxypregn-4-ene-3,20-dione, Glucocorticoid, Receptor, Immunosuppressants, Glucocorticoid, Receptor, Tocris Bioscience

Citations for Hydrocortisone

Citations are publications that use Tocris products.

Currently there are no citations for Hydrocortisone. Do you know of a great paper that uses Hydrocortisone from Tocris? If so please let us know.

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Literature in this Area

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Pathways for Hydrocortisone

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