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Adrenal glucocorticoid released in the stress response. Increases glucose production by gluconeogenesis. Immunosuppressant and antidiuretic hormone.
|Storage||Store at RT|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
|Solvent||Max Conc. mg/mL||Max Conc. mM|
Preparing Stock Solutions
The following data is based on the product molecular weight 362.46. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||2.76 mL||13.79 mL||27.59 mL|
|5 mM||0.55 mL||2.76 mL||5.52 mL|
|10 mM||0.28 mL||1.38 mL||2.76 mL|
|50 mM||0.06 mL||0.28 mL||0.55 mL|
References are publications that support the biological activity of the product.
Khani and Tayek (2001) Cortisol increases gluconeogenesis in humans; its role in the metabolic syndrome. Clin.Sci.(Lond) 101 739 PMID: 11724664
If you know of a relevant reference for Hydrocortisone, please let us know.
Keywords: Hydrocortisone, Hydrocortisone supplier, glucocorticoids, antiinflammatory, stress, induces, inducers, gluconeogenesis, adrenal, gland, 11b,17a,21-Trihydroxypregn-4-ene-3,20-dione, Glucocorticoid, Receptor, Immunosuppressants, 4093, Tocris Bioscience
2 Citations for Hydrocortisone
Citations are publications that use Tocris products. Selected citations for Hydrocortisone include:
Srinivasan et al (2018) Androgen receptor expression reduces stemness characteristics of prostate cancer cells (PC3) by repression of CD44 and SOX2. J Cell Biochem PMID: 30206982
Frost et al (2017) The Use of DQ-BSA to Monitor the Turnover of Autophagy-Associated Cargo. Methods Enzymol 587 43 PMID: 28253971
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Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* or download your copy today!
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Major depressive disorder is characterized by depressed mood and a loss of interest and/or pleasure. Updated in 2015 this poster highlights presynaptic and postsynaptic targets for the potential treatment of major depressive disorder, as well as outlining the pharmacology of currently approved antidepressant drugs.