Cell Cycle Inhibitor Other
| Cat. No. | Product Name / Activity |
|---|---|
| 4406 | 10058-F4 |
| Arrests cell cycle at G0/G1 | |
| 4138 | ABT 751 |
| Inhibitor of microtubule polymerization; blocks cell cycle at G2M | |
| 6827 | Artesunate |
| Arrests cell cycle in G2/M; antimalarial | |
| 3968 | AZD 5438 |
| Blocks cell cycling at G2-M, S and G1 phases | |
| 1761 | Baicalein |
| Induces G1 and G2 cell cycle arrest. Also lipoxygenase inhibitor | |
| 5144 | CFM 4 |
| CARP-1 mimetic; induces G2/M cell cycle arrest | |
| 4436 | 8-Chloroadenosine |
| Cytotoxic nucleoside analog; induces G2/M arrest | |
| 5800 | CHMFL-FLT3-122 |
| Arrests cell cycle in G0/G1; FLT3 inhibitor | |
| 5331 | CPI 203 |
| Arrests cell cycle at G1 phase; also BET bromodomain inhibitor | |
| 1417 | Daidzein |
| Arrests cell cycle in G1 phase | |
| 4502 | DIM |
| Activates Chk2; induces G2/M cell cycle arrest | |
| 3502 | Epothilone B |
| Microtubule stabilization agent; promotes G2-M cell cycle arrest | |
| 7303 | iHAP1 New |
| Arrests cell cycle in prometaphase; allosteric activator of PP2A | |
| 1813 | Indirubin-3'-oxime |
| Induces cell cycle arrest, antiproliferative | |
| 6782 | Indisulam |
| Arrests cell cycle at G1 phase; molecular glue | |
| 1230 | Methotrexate |
| Cytotoxic agent | |
| 5231 | MPC 6827 hydrochloride |
| Inhibitor of microtubule polymerization; antimitotic and antitumor | |
| 3715 | Narciclasine |
| Antiproliferative agent; slows cell cycle progression | |
| 6070 | Pladienolide B |
| Arrests cell cycle in G1 and G2/M; mRNA splicing inhibitor | |
| 4761 | Plumbagin |
| Induces G2/M cell cycle arrest; anticancer | |
| 4763 | Pyridostatin pentahydrochloride |
| Stabilizes G-quadruplexes; induces DNA damage and cell cycle arrest | |
| 4817 | SKPin C1 |
| Inhibits Skp2-mediated p27 degradation; induces cell cycle arrest | |
| 5264 | Temsirolimus |
| mTOR inhibitor; arrests cell cycle at G1/S | |
| 3909 | Toceranib |
| Potent PDGFR and VEGFR inhibitor; induces cell cycle arrest | |
| 4282 | WYE 687 dihydrochloride |
| Potent and selective mTOR inhibitor; induces G1 cell cycle arrest | |
| 5493 | XL 413 hydrochloride |
| Potent and selective Cdc7 inhibitor | |
| 4307 | YC 1 |
| Soluble guanylyl cyclase (sGC) activator; induces G1 cell cycle arrest |
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Our Cell Cycle & DNA Damage Repair poster summarizes the stages of the cell cycle and DNA repair. It also highlights strategies for enhancing replicative stress in cancer cells to force mitotic catastrophe and cell death.
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