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ETB Receptors

The endothelinB receptor (ETB receptor) is a member of the endothelin receptor group of G-protein-coupled receptors that also includes ETA. They are located primarily in vascular endothelial cells where they play a role in vasoconstriction, vasodilation and cell proliferation.

Products
Background
Literature (4)
Gene Data

ETB Receptor Agonists
Cat. No. Product Name / Activity
1189 BQ-3020
Selective ETB agonist
1196 IRL-1620
Highly selective ETB agonist
1175 Sarafotoxin S6c
Selective ETB agonist

ETB Receptor Antagonists
Cat. No. Product Name / Activity
1500 BQ 788 sodium salt
Selective ETB antagonist
1838 IRL-2500
Potent ETB antagonist

Related Targets

The endothelinB receptor (ETB receptor) is a member of the endothelin receptor group of G-protein-coupled receptors that also includes ETA. They are located primarily in the vascular endothelial cells where they play a role in vasoconstriction, vasodilation, bronchoconstriction and cell proliferation. The human ETB receptor gene has been localized to chromosome 13 (13q22).

External sources of pharmacological information for ETB Receptors :

Literature for ETB Receptors

Tocris offers the following scientific literature for ETB Receptors to showcase our products. We invite you to request* your copy today!

*Please note that Tocris will only send literature to established scientific business / institute addresses.

Cardiovascular Research Product Guide

Cardiovascular Research Product Guide

A collection of over 250 products for cardiovascular research, the guide includes research tools for the study of:

  • Hypertension
  • Thrombosis and Hemostasis
  • Atherosclerosis
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  • Heart Failure
GPCR Product Listing

GPCR Product Listing

A collection of over 450 products for G protein-coupled receptors, the listing includes research tools for the study of:

  • Rhodopsin-like Receptors
  • Glutamate Receptors
  • Frizzled Receptors
  • GPCR Signaling
Peptide Hormone Receptors Product Listing

Peptide Hormone Receptors Product Listing

A collection of over 200 products for peptide hormone receptors, the listing includes research tools for the study of:

  • Anterior Pituitary Regulation
  • Blood Pressure Regulation
  • Feeding and Appetite Regulation
  • Glucose Regulation
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Cardiovascular Poster

Cardiovascular Poster

Cardiovascular disease remains one of the major causes of morbidity and mortality in the Western world and therefore this therapeutic area continues to be of great interest to researchers. This poster highlights the key GPCRs regulating vascular reactivity.

ETB Receptor Gene Data

Species Gene Symbol Gene Accession No. Protein Accession No.
Human EDNRB NM_003991 P24530
Mouse EdnrB NM_007904 P48302
Rat EdnrB NM_017333 P21451