ETA Receptors
The endothelinA receptor (ETA receptor) is a member of the endothelin receptor group of G-protein-coupled receptors that also includes ETB. They are located primarily in the vascular smooth muscle where they play a role in vasoconstriction and cell proliferation.
ETA Receptor Antagonists |
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|---|---|
| Cat. No. | Product Name / Activity |
| 5730 | A 127722 |
| Highly potent, selective ETA antagonist; orally bioavailable | |
| 5828 | Ambrisentan |
| Selective ETA antagonist | |
| 1188 | BQ-123 |
| Selective ETA antagonist | |
| 2942 | CI 1020 |
| Highly selective, orally active ETA antagonist | |
The endothelinA receptor (ETA receptor) is a member of the endothelin receptor group of G-protein-coupled receptors that also includes ETB. They are located primarily in the vascular smooth muscle where they play a role in vasoconstriction and cell proliferation. The human ETA receptor gene has been localized to chromosome 4 (4q31.22).
External sources of pharmacological information for ETA Receptors :
Literature for ETA Receptors
Tocris offers the following scientific literature for ETA Receptors to showcase our products. We invite you to request* your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.
Cardiovascular Research Product Guide
A collection of over 250 products for cardiovascular research, the guide includes research tools for the study of:
- Hypertension
- Thrombosis and Hemostasis
- Atherosclerosis
- Myocardial Infarction
- Ischemia/Reperfusion Injury
- Arrhythmias
- Heart Failure
GPCR Product Listing
A collection of over 450 products for G protein-coupled receptors, the listing includes research tools for the study of:
- Rhodopsin-like Receptors
- Glutamate Receptors
- Frizzled Receptors
- GPCR Signaling
Peptide Hormone Receptors Product Listing
A collection of over 200 products for peptide hormone receptors, the listing includes research tools for the study of:
- Anterior Pituitary Regulation
- Blood Pressure Regulation
- Feeding and Appetite Regulation
- Glucose Regulation
- Peptide Hormone Processing
Cardiovascular Poster
Cardiovascular disease remains one of the major causes of morbidity and mortality in the Western world and therefore this therapeutic area continues to be of great interest to researchers. This poster highlights the key GPCRs regulating vascular reactivity.
Pain Poster
Peripheral sensitization is the reduction in the threshold of excitability of sensory neurons that results in an augmented response to a given external stimulus. This poster outlines the excitatory and inhibitory signaling pathways involved in modulation of peripheral sensitization. The role of ion channels, GPCRs, neurotrophins, and cytokines in sensory neurons are also described.
Our Cardiovascular Guide highlights over 250 products for cardiovascular research.
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Our Peptide Hormone Receptors Listing highlights over 200 products for peptide hormone receptors.
Request copyRequest PDFWritten by J.J. Maguire and A.P. Davenport
Our Cardiovascular poster highlights the key G protein-coupled receptors involved in the regulation of vascular reactivity.
Request copyDownload PDFWritten by Grant D. Nicol and Michael R. Vasko
Our Peripheral Sensitization poster gives a summary of the excitatory and inhibitory signaling pathways involved in modulation of peripheral sensitization.
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