Bradykinin Receptors
Bradykinin and related kinins are a family of small peptides which act as mediators of pain and inflammation. They exert a variety of biological effects on the endothelium and peripheral circulation through their action on two bradykinin receptor subtypes: B1 and B2.
Agonists |
Cat. No. | Product Name / Activity |
|---|---|
| 2371 | Bombinakinin M |
| Potent bradykinin agonist | |
| 3004 | Bradykinin |
| Endogenous agonist at bradykinin receptors (B2 > B1) | |
| 3230 | Sar-[D-Phe8]-des-Arg9-Bradykinin |
| Potent and selective B1 agonist | |
| 3229 | [Phe8Ψ(CH-NH)-Arg9]-Bradykinin |
| Selective B2 agonist | |
| 3225 | Lys-[Des-Arg9]Bradykinin |
| Selective B1 agonist | |
Antagonists |
Cat. No. | Product Name / Activity |
| 3014 | HOE 140 |
| Potent and selective B2 antagonist | |
| 3978 | MEN 11270 |
| Selective B2 antagonist; analog of HOE 140 (Cat. No. 3014) | |
| 1697 | Noscapine hydrochloride |
| Bradykinin antagonist; also tubulin inhibitor | |
| 3407 | R 715 |
| Potent and selective B1 antagonist | |
| 3226 | R 892 |
| Potent and selective B1 antagonist | |
| 1057 | WIN 64338 hydrochloride |
| Bradykinin B2 antagonist | |
Other |
Cat. No. | Product Name / Activity |
| 2370 | Bombinakinin-GAP |
| Bioactive, bradykinin-related peptide | |
Bradykinin and related kinins are a family of small peptides which act as mediators of pain and inflammation. They exert a variety of biological effects on the endothelium and peripheral circulation through their action on two G-protein-coupled bradykinin receptor subtypes, the B1 receptor and the B2 receptor. Bradykinin is an important pro-inflammatory molecule that causes vasodilation, plasma protein extravasation, smooth muscle contraction and pain.
External sources of pharmacological information for Bradykinin Receptors :
Literature for Bradykinin Receptors
Tocris offers the following scientific literature for Bradykinin Receptors to showcase our products. We invite you to request* or download your copy today!
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Cardiovascular disease remains one of the major causes of morbidity and mortality in the Western world and therefore this therapeutic area continues to be of great interest to researchers. This poster highlights the key GPCRs regulating vascular reactivity.
Our Pain guide highlights over 280 products for Pain research.
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Our Peptide Hormone Receptors Listing highlights over 200 products for peptide hormone receptors.
Request copyDownload PDFWritten by J.J. Maguire and A.P. Davenport
Our Cardiovascular poster highlights the key G protein-coupled receptors involved in the regulation of vascular reactivity.
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