Bradykinin

Pricing Availability   Qty
Description: Endogenous agonist at bradykinin receptors (B2 > B1)
Purity: ≥95% (HPLC)
Datasheet
Citations (7)
Reviews
Literature (4)

Biological Activity for Bradykinin

Bradykinin is an endogenous bradykinin receptor agonist that displays selectivity for B2 over B1 receptors. Proinflammatory peptide.

Technical Data for Bradykinin

M. Wt 1060.22
Formula C50H73N15O11
Sequence RPPGFSPFR
Storage Store at -20°C
Purity ≥95% (HPLC)
CAS Number 58-82-2
PubChem ID 439201
InChI Key QXZGBUJJYSLZLT-FDISYFBBSA-N
Smiles [H]N[C@@H](CCCNC(N)=N)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)NCC(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CO)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CCCNC(N)=N)C(O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility Data for Bradykinin

Solubility Soluble to 1 mg/ml in water

Product Datasheets for Bradykinin

Certificate of Analysis / Product Datasheet
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References for Bradykinin

References are publications that support the biological activity of the product.

Regoli et al (1998) Bradykinin receptors and their antagonists. Eur.J.Pharmacol. 348 1 PMID: 9650825

Leeb-Lundberg et al (2005) International union of pharmacology XLV. Classification of the kinin receptor family: from molecular mechanisms to pathophysiological consequences. Pharmacol.Rev. 57 27 PMID: 15734727

Abraham et al (2006) Peptide and non-peptide bradykinin receptor antagonists: role in allergic airway disease Eur.J.Pharmacol. 533 215 PMID: 16455073


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View Related Products by Product Action

View all Bradykinin Receptor Agonists

Keywords: Bradykinin, Bradykinin supplier, Endogenous, agonists, bradykinin, receptors, B2, B1, Receptors, Bradykinin, 3004, Tocris Bioscience

7 Citations for Bradykinin

Citations are publications that use Tocris products. Selected citations for Bradykinin include:

Hannedouche et al (2013) Identification of the C3a receptor (C3AR1) as the target of the VGF-derived peptide TLQP-21 in rodent cells. Proc Natl Acad Sci U S A 288 27434 PMID: 23940034

Zhang (2019) Direct Gαq Gating Is the Sole Mechanism for TRPM8 Inhibition Caused by Bradykinin Receptor Activation. Cell Rep 27 3672 PMID: 31216483

Zakaria et al (2014) Antinociceptive activity of methanolic extract of Muntingia calabura leaves: further elucidation of the possible mechanisms. BMC Complement Altern Med 14 63 PMID: 24555641

Bell et al (2014) Retinal vasculature of adult zebrafish: in vivo imaging using confocal scanning laser ophthalmoscopy. Exp Eye Res 129 107 PMID: 25447564


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Reviews for Bradykinin

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Literature in this Area

Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!

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