Bradykinin

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Description: Endogenous agonist at bradykinin receptors (B2 > B1)
Purity: ≥95% (HPLC)
Datasheet
Citations (7)
Reviews

Biological Activity for Bradykinin

Bradykinin is an endogenous bradykinin receptor agonist that displays selectivity for B2 over B1 receptors. Proinflammatory peptide.

Technical Data for Bradykinin

M. Wt 1060.22
Formula C50H73N15O11
Sequence RPPGFSPFR
Storage Store at -20°C
Purity ≥95% (HPLC)
CAS Number 58-82-2
PubChem ID 439201
InChI Key QXZGBUJJYSLZLT-FDISYFBBSA-N
Smiles [H]N[C@@H](CCCNC(N)=N)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)NCC(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CO)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CCCNC(N)=N)C(O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility Data for Bradykinin

Solubility Soluble to 1 mg/ml in water

Product Datasheets for Bradykinin

Certificate of Analysis / Product Datasheet
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References for Bradykinin

References are publications that support the biological activity of the product.

Regoli et al (1998) Bradykinin receptors and their antagonists. Eur.J.Pharmacol. 348 1 PMID: 9650825

Leeb-Lundberg et al (2005) International union of pharmacology XLV. Classification of the kinin receptor family: from molecular mechanisms to pathophysiological consequences. Pharmacol.Rev. 57 27 PMID: 15734727

Abraham et al (2006) Peptide and non-peptide bradykinin receptor antagonists: role in allergic airway disease Eur.J.Pharmacol. 533 215 PMID: 16455073


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Keywords: Bradykinin, Bradykinin supplier, Endogenous, agonists, bradykinin, receptors, B2, B1, Receptors, Bradykinin, 3004, Tocris Bioscience

7 Citations for Bradykinin

Citations are publications that use Tocris products. Selected citations for Bradykinin include:

Jakubowska et al (2016) Nitric oxide signals are interlinked with calcium signals in normal pancreatic stellate cells upon oxidative stress and inflammation. Open Biol. 6 160149 PMID: 27488376

Kirkby et al (2012) Cyclooxygenase-1, not cyclooxygenase-2, is responsible for physiological production of prostacyclin in the cardiovascular system. Gastroenterology 109 17597 PMID: 23045674

Zakaria et al (2014) Antinociceptive activity of methanolic extract of Muntingia calabura leaves: further elucidation of the possible mechanisms. BMC Complement Altern Med 14 63 PMID: 24555641

Bell et al (2014) Retinal vasculature of adult zebrafish: in vivo imaging using confocal scanning laser ophthalmoscopy. Exp Eye Res 129 107 PMID: 25447564


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