Angiotensin AT2 Receptors

The angiotensin2 receptor (AT2) is a member of the angiotensin receptor group of G-protein-coupled receptors that also includes AT1 and AT4. They are located primarily in the brain, adrenal medulla, heart and uterus where they counterbalance the effects of AT1.

Products
Background
Literature
Gene Data

Agonists

Cat No Product Name / Activity
3615 Novokinin
Orally active AT2 agonist

Antagonists

Cat No Product Name / Activity
1361 PD 123319 ditrifluoroacetate
Potent, selective non-peptide AT2 antagonist

Other

Cat No Product Name / Activity
2569 CGP 42112
Selective, high affinity AT2 ligand

The angiotensin2 receptor (AT2) is a member of the angiotensin receptor group of G-protein-coupled receptors that also includes AT1 and AT4. They are located primarily in the brain, adrenal medulla, heart and uterus where they counterbalance the effects of the AT1 receptor. The human AT2 receptor gene has been localized to chromosome X (Xq22-q23).

External sources of pharmacological information for Angiotensin AT2 Receptors :

Literature for Angiotensin AT2 Receptors

Cardiovascular

Cardiovascular Research Product Guide

A collection of over 250 products for cardiovascular research, the guide includes research tools for the study of:

  • Hypertension
  • Thrombosis and Hemostasis
  • Atherosclerosis
  • Myocardial Infarction
  • Ischemia/Reperfusion Injury
  • Arrhythmias
  • Heart Failure
GPCR

GPCR Product Listing

A collection of over 450 products for G protein-coupled receptors, the listing includes research tools for the study of:

  • Rhodopsin-like Receptors
  • Secretin-like Receptors
  • Glutamate Receptors
  • Frizzled Receptors
  • GPCR Signaling
Peptide Hormone Receptors

Peptide Hormone Receptors Product Listing

A collection of over 200 products for peptide hormone receptors, the listing includes research tools for the study of:

  • Anterior Pituitary Regulation
  • Blood Pressure Regulation
  • Feeding and Appetite Regulation
  • Glucose Regulation
  • Peptide Hormone Processing
Cardiovascular

Cardiovascular Poster

Cardiovascular disease remains one of the major causes of morbidity and mortality in the Western world and therefore this therapeutic area continues to be of great interest to researchers. This poster highlights the key GPCRs regulating vascular reactivity.

Angiotensin AT2 Receptor Gene Data

Species Gene Symbol Gene Accession No. Protein Accession No.
Human AGTR2 NM_000686 P50052
Mouse Agtr2 NM_007429 P35374
Rat Agtr2 NM_012494 P35351