Hydroxycarboxylic Acid Receptors

More Information »Hydroxycarboxylic acid (HCA) receptors are Gi/Go protein-coupled receptors for which hydroxycarboxylic acids are endogenous ligands. Three HCA receptors are known to exist: HCA1 (GPR81), HCA2 (GPR109A) and HCA3 (GPR109B).

Hydroxycarboxylic Acid Receptor Products

Product Name / Activity
1762 Acifran
Hypolipidemic agent; agonist for the GPR109A (HM74A) and GPR109B receptors
4599 3,5-DHBA
Selective HCA1 agonist
2469 IBC 293
Selective agonist for the GPR109B (HM74) receptor. Antilipolytic
4881 LUF 6283
HCA2 (GPR109A) partial agonist
4622 MK 1903
Potent and selective GPR109A (HCA2) agonist
4511 MMF
Activator of Nrf2 pathway; GPR109A agonist
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