TA 02

Discontinued Product

TA 02 (Cat. No. 5384) has been withdrawn from sale for commercial reasons.
Cat.No. 5384 - TA 02 | C20H13F2N3
Description: Induces cardiomyocyte differentiation from hESCs
Chemical Name: 4-(2-(2-Fluorophenyl)-4-(fluorophenyl)-1H-imidazol-5-yl)pyridine
Purity: ≥98% (HPLC)
Datasheet
Citations
Reviews
Literature

Biological Activity

Induces cardiomyocyte differentiation from human embryonic stem cells following mesoderm induction. Potently inhibits p38α, CK1δ and CK1ε (IC50 values are 20, 32 and 32 nM respectively).

Licensing Information

Sold under agreement from the Agency for Science, Technology and Research (A*STAR), ETPL, and affiliates including the Bioprocessing Technology Institute.

Technical Data

M. Wt 333.33
Formula C20H13F2N3
Storage Store at +4°C
Purity ≥98% (HPLC)
PubChem ID 91691130
InChI Key QIFJOFNVIVQRNJ-UHFFFAOYSA-N
Smiles FC(C=C4)=CC=C4C(N=C(C3=C(F)C=CC=C3)N2)=C2C1=CC=NC=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

References

References are publications that support the biological activity of the product.

Laco et al (2014) Cardiomyocyte differentiation of pluripotent stem cells with SB203580 analogues correlates with Wnt pathway CK1 inhibition independent of p38 MAPK signaling. J.Mol.Cell.Cardiol PMID: 25528965

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Citations for TA 02

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Currently there are no citations for TA 02.

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