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Fluorescent dual α9β1/α4β1 integrin inhibitor. Comprises BOP (Cat. No. 6047) conjugated to Janelia Fluor® 646 (Cat. No. 6148). Fluorogenic: fluoresces only once bound to integrins, enabling hassle-free no-wash experiments. Bright and photostable, enabling live cell tracking of integrin receptors over long time-course experiments. Excitation maximum = 655 nm; emission maximum = 672 nm.
Application of BOP-JF646 in Immortalized Human Keratinocyte Cells
Immortalized human keratinocyte cells expressing a GFP-tagged α4 integrin were treated with 10 μM BOP-Janelia Fluor® 646. Cells were incubated at 37°C and imaged using a Nikon A1R confocal microscope. Scale bar = 10 μm.
Image kindly provided by Willow Hight-Warburton, Kings College London.
Optical Data for BOP-JF646
|Storage||Store at -20°C|
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Keywords: BOP-JF646, BOP-JF646 supplier, Fluorescent, dual, α9β1/α4β1, integrins, inhibitors, BOP, labels, stains, HSC, progenitors, hematopoietic, stem, cells, Integrins, Stem, Cell, Signaling, Integrin, Probes, 6997, Tocris Bioscience
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