Ras GTPase Inhibitors

Cat. No. Product Name / Activity
7713 AMG 510
Potent and selective KRASG12C inhibitor
6857 BAY 293
Potent KRas/SOS1 interaction inhibitor
6791 BC-LI-0186
Leucyl-tRNA synthase (TRS)/Ras-related GTP-binding protein D (RagD) interaction inhibitor
6407 Fendiline Hydrochloride
Inhibits KRas localization to the plasma membrane; also L-type calcium channel blocker
5607 GNF 7
Ras signaling inhibitor; inhibits Ack1 and GCK
7928 KRpep-2d
Potent and selective KRASG12D inhibitor
6429 ML 210
Selectively kills mutant HRAS-expressing cells; glutathione peroxidase inhibitor; induces ferroptosis
7488 MRTX 849
Mutation-selective inhibitor of KRASG12C
5411 RBC8
RalA and RalB inhibitor
6111 Zoledronic Acid
Ras signaling inhibitor; also potent farnesyl diphosphate (FPP) synthase inhibitor