5-HT1D Receptors
Serotonin 5-HT1D receptors, previously known as 5-HT1Dα receptors, are located primarily in the basal ganglia, hippocampus, cortex, spinal cord and vascular smooth muscle cells. 5-HT1D receptors are thought to be involved in neuropsychiatric disorders such as depression.
5-HT1D Receptor Agonists |
|
|---|---|
| Cat. No. | Product Name / Activity |
| 1985 | PNU 142633 |
| Highly selective 5-HT1D agonist | |
| 5136 | Rizatriptan benzoate |
| Potent 5-HT1B and 5-HT1D agonist | |
| 3586 | Sumatriptan succinate |
| 5-HT1A, 5-HT1B and 5-HT1D agonist | |
| 4657 | Zolmitriptan |
| Potent 5-HT1B/1D/1F agonist | |
5-HT1D Receptor Antagonists |
|
| Cat. No. | Product Name / Activity |
| 1477 | GR 127935 hydrochloride |
| Potent and selective 5-HT1B and 5-HT1D antagonist | |
| 3078 | LY 310762 hydrochloride |
| Selective 5-HT1D antagonist | |
Serotonin 5-HT1D receptors, previously known as 5-HT1Dα receptors, are located primarily in the basal ganglia, hippocampus, cortex, spinal cord and vascular smooth muscle cells. 5-HT1D receptors are thought to be involved in neuropsychiatric disorders such as depression.
External sources of pharmacological information for 5-HT1D Receptors :
Literature for 5-HT1D Receptors
Tocris offers the following scientific literature for 5-HT1D Receptors to showcase our products. We invite you to request* your copy today!
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GPCR Product Listing
A collection of over 450 products for G protein-coupled receptors, the listing includes research tools for the study of:
- Rhodopsin-like Receptors
- Glutamate Receptors
- Frizzled Receptors
- GPCR Signaling
5-HT Receptors Scientific Review
Written by Nicholas M. Barnes and John F. Neumaier, this review summarizes the various serotonin receptor subtypes and their importance in mediating the role of serotonin in numerous physiological and pharmacological processes. Compounds available from Tocris are listed.
Our 5-HT review summarizes the serotonin receptor subtypes and highlights their importance in mediating various physiological & pharmacological processes.
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