NF-κB and IκB Inhibitors
| Cat. No. | 产品名称/活性 |
|---|---|
| 4547 | ACHP |
| Selective IKKα and IKKβ inhibitor; blocks NF-κB-DNA binding | |
| 4857 | Amlexanox |
| Inhibitor of TBK1 and IKKε; antiallergic agent | |
| 1777 | Arctigenin |
| Inhibitor of IκBα phosphorylation. Also inhibits MEK1 | |
| 1743 | Bay 11-7085 |
| Irreversible inhibitor of TNF-α-induced IκBα phosphorylation | |
| 4806 | BMS 345541 |
| Selective allosteric inhibitor of IKK; anti-inflammatory | |
| 5821 | C-DIM 12 |
| Inhibits NF-κB-dependent gene expression; Nurr1 activator | |
| 2743 | Caffeic acid phenethyl ester |
| Specific inhibitor of NF-κB activation | |
| 3203 | Celastrol |
| Inhibits TNF-α-induced NF-κB activation | |
| 6237 | FPS ZM1 |
| High affinity antagonist of the receptor for advanced glycation end products (RAGE) | |
| 5672 | GSK 319347A |
| Potent and selective IKKε inhibitor | |
| 2539 | IKK 16 |
| Selective inhibitor of IKK | |
| 2611 | IMD 0354 |
| Inhibitor of IKKβ | |
| 5699 | IP7e |
| Blocks NF-κB pathway; also potent Nurr1 activator | |
| 2874 | Luteolin |
| Blocks NF-κB activation | |
| 1748 | MG 132 |
| Inhibits NF-κB activation; proteasome and calpain inhibitor | |
| 4899 | ML 120B dihydrochloride |
| Novel IKK2-selective inhibitor | |
| 7136 | NIKi |
| Potent NIK inhibitor | |
| 4238 | PF 184 |
| Potent and selective IKKβ inhibitor | |
| 5309 | SP 100030 |
| NF-κB and AP-1 dual inhibitor | |
| 4935 | Sulfasalazine |
| Inhibitor of NF-κB activation; also inhibits SXC and folate transporter 1 | |
| 2559 | TPCA-1 |
| Potent, selective inhibitor of IKKβ | |
| 6111 | Zoledronic Acid |
| NF-κB signaling inhibitor; also potent farnesyl diphosphate (FPP) synthase inhibitor |