Tocriscreen™ Compound Libraries
The Tocriscreen™ range of bioactive compound libraries are collections of compounds designed for use in screening assays for receptor de-orphaning, target validation, drug re-profiling, tool compound identification and also assay development. Comprised of high-purity compounds selected from the Tocris catalog, these libraries provide wide coverage of cellular targets, including GPCRs, ion channels, kinases, enzymes, nuclear receptors and transporters.
To request the detailed compound lists for any of the Tocriscreen compound libraries, please complete the compound library inquiry form.
Libraries |
|
| Cat. No. | 产品名称/活性 |
|---|---|
| 7152 | Tocriscreen 2.0 Micro |
| Bioactive compound library for high-throughput screening, high-content screening, target validation and assay development; comprised of 1280 biologically active compounds (15 μL 10 mM DMSO solutions) | |
| 7151 | Tocriscreen 2.0 Mini |
| Bioactive compound library for high-throughput screening, high-content screening, target validation and assay development; comprised of 1280 compounds (50 μL 10 mM DMSO solutions) | |
| 7578 | Tocriscreen Epigenetics 3.0 |
| A library of 160 epigenetic compounds (100 μL, 10 mM DMSO solutions) for high throughput screening, high content screening, target validation and assay development | |
| 8100 | Tocriscreen GPCR Compound Library |
| A bioactive compound library of 240 GPCR compounds (100 μL 10 mM DMSO solutions) for high-throughput screening, high-content screening, target validation and assay development | |
| 7340 | Tocriscreen Stem Cell Library |
| A library of 120 stem cell compounds (100 μL 10 mM DMSO solutions) to explore stem cell reprogramming, differentiation, proliferation and signaling | |
- Compounds ready-to-use in DMSO (10 mM)
- Key research areas are covered including Cancer, Epigenetics, Neuroscience and Stem Cells
- Includes commonly used standards and the latest research tools, as well pharmacologically active components of FDA-approved drug formulations
- Compounds available for re-supply from the Tocris catalog
Resources for Tocriscreen Compound Libraries
The Chemical Diversity of the Tocriscreen Kinase Inhibitor 3.0
The images show the overlapping chemical space of the 210 compounds in the Tocriscreen Kinase Inhibitor 3.0 compound library (green dots) in relation to the chemical space occupied by the ChEMBL Kinase Inhibitors (grey dots). Each dot represents a unique fingerprint generated from each compound's 3D molecular structure. The even distribution of the fingerprints of the compounds in the Tocriscreen Kinase Inhibitor 3.0 compound library highlights the chemical diversity of this library.
Webinar: Chemical Genomics - Undruggables and the Quest for Therapeutics
This webinar brings together experts to discuss chemical genomics and the advances and promises it brings to therapeutic discovery. The use of compound libraries and the possibilities for drug repurposing are examined, and the potential of patient lead approaches to identify novel targets with chemical genomics are considered.
Watch Chemical Genomics Webinar