New Products

View all new products by date added

Search for new products by date added, alphabetically, or by pharmacological action.

New products are an essential component of our range. Introductions are made on an ongoing basis, with hundreds of new small molecules and peptides being added every year. Our aim is to find the latest, otherwise unobtainable research tools, and bring them to the market as quickly as we can. New products can be identified throughout the Tocris website by the symbol.

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Cat. No. 产品名称/活性 Date Added
6858 MMG 11 Jan 2020
TLR2 antagonist
TB3748-GMP XAV 939 Jan 2020
XAV 939 synthesized to cGMP guidelines
6925 NBC 6 Jan 2020
NLRP3 inflammasome inhibitor
6952 VH 101, phenol Jan 2020
Hydroxyl functionalized VHL ligand
6964 LY 2119620 Jan 2020
Positive allosteric modulator of M2 and M4 receptors
7152 Tocriscreen 2.0 Micro Jan 2020
A library of 1280 biologically active compounds (15 μL 10 mM DMSO solutions)
6985 VH 032 - linker 13 Jan 2020
VH 032 - alkylC5 amine
7151 Tocriscreen 2.0 Mini Jan 2020
A library of 1280 biologically active compounds (50 μL 10 mM DMSO solutions)
7051 Tasquinimod Jan 2020
High affinity HDAC4 negative allosteric modulator; also binds S100A9; antiangiogenic
7007 PDD 00017238 Dec 2019
High affinity and potent PARG inhibitor
7009 PDD 00031705 Dec 2019
Negative control for PDD 00017238 (Cat. No. 7007).
6725 CHDI 00390576 Dec 2019
Potent and selective class IIa HDAC inhibitor; brain penetrant
6931 AF 64394 Dec 2019
Potent and selective GPR3 inverse agonist
7049 Nintedanib Dec 2019
Potent VEGFR, PDGFR and FGFR inhibitor
6586 Targapremir 210 Dec 2019
Inhibits formation of miR-210
6991 Poly Vinyl Alcohol Dec 2019
Carrier molecule for stem cell culture; replaces serum albumin for ex vivo stem cell expansion
7026 Veliparib dihydrochloride Dec 2019
High affinity PARP-1 and -2 inhibitor; orally bioavailable
7071 GSK 2239633A Dec 2019
Potent CCR4 antagonist
7002 KYA 1797K Dec 2019
Wnt/β-catenin signaling inhibitor
6860 SB 290157 trifluoroacetate Dec 2019
Potent C3a receptor antagonist
6961 FzM1.8 Dec 2019
Frizzled 4 allosteric agonist; exhibits biased siginaling; preserves stemness
7050 Ribociclib Dec 2019
Dual cdk4/cdk6 inhibitor; orally bioavailable
6875 TRPC6-PAM-C20 Dec 2019
Selective TRPC6 positive allosteric modulator
6981 TL 0259 Dec 2019
Selective and highly potent Fgr and Lyn kinase inhibitor; orally bioavailable
6729 TAN 452 Dec 2019
Potent and selective peripherally acting δ opioid antagonist; antianalgesic.
6775 ST 045849 Dec 2019
O-GlcNAc transferase (OGT) inhibitor
6900 NNMTi Dec 2019
Nicotinamide N-methyltransferase (NNMT) inhibitor; promotes myoblast differentiation
7053 MM 07 Dec 2019
Apelin receptor biased agonist; exhibits bias for the G protein pathway
6912 dTAG-7 Dec 2019
First generation Degrader for mutant FKBP12F36V fusion proteins; useful alternative to genetic methods for target validation
6799 MB 0223 Dec 2019
Dynamin-related GTPase DRP1 partial inhibitor
5860 7rh Dec 2019
Potent and selective DDR1 inhibitor; orally bioavailable
6946 Thalidomide amide-alkylC8-amine Nov 2019
Thalidomide-alkylC8-amine
6474 A 410099.1 amide-alkylC4-amine Nov 2019
A 410099.1 amide-alkylC4-amine
6471 A 410099.1, amine Nov 2019
Functionalized IAP ligand for PROTACs
7070 Mirabegron Nov 2019
Potent and selective β3 agonist
7031 Amyloid β-Peptide (1-37) (human) Nov 2019
Amyloid β-protein fragment
7119 Sorbic acid Nov 2019
Activator of hFFA2-DREADDs
6472 A 410099.1 amide-PEG3-amine Nov 2019
A 410099.1 amide-PEG3-amine
6473 A 410099.1 amide-PEG2-amine Nov 2019
A 410099.1 amide-PEG2-amine
6971 aTAG 4531 Nov 2019
Degrader of MTH1 fusion proteins for use within the aTAG system
6870 AZ 12799734 Nov 2019
Potent TGF-βRI inhibitor
7013 OptoBI-1 Nov 2019
Photoswitchable TRPC3/6/7 agonist
6863 N6-Cyclohexyladenosine Nov 2019
High affinity A1 receptor agonist
7066 RCGD 423 Nov 2019
gp130 modulator; activates JAK/STAT signaling
7044 (±)-α-Lipoic acid Nov 2019
Liquid-liquid phase separated condensate modifier; reduces stress granule formation
4265 AS 1842856 Nov 2019
Potent and selective Foxo1 inhibitor; orally bioavailable
6481 AP 14145 hydrochloride Nov 2019
KCa2 channel negative allosteric modulator
6895 VU 0424465 Oct 2019
Potent mGlu5 positive allosteric modulator and agonist; binds allosteric site with high affinity
6847 TAT-GluA2 3Y Oct 2019
Inhibitor of AMPA receptor endocytosis
6691 LP 922056 Oct 2019
Notum inhibitor; activates Wnt signaling
6574 Fluorescein-NAD+ Oct 2019
Fluorescent NAD+; substrate for ADP-ribosylation for use in PARP assays
7065 Kainic acid (synthetic) Oct 2019
Kainate agonist; excitant and neurotoxin
7045 (±)-α-Lipoamide Oct 2019
Phase-separated condensate modifier; orally bioavailable
6982 Cyclosporin H Oct 2019
Enhances lentiviral transduction
6936 VZ 185 Oct 2019
Potent and selective BRD7/9 Degrader
6932 VU 0467485 Oct 2019
Potent and selective positive allosteric modulator of M4 receptors; orally bioavailable and brain penetrant
6897 P110 Oct 2019
Dynamin-related protein 1 (Drp1) inhibitor; cell-permeable
6974 BMS 986094 Oct 2019
Prodrug of HCV RNA polymerase inhibitor 2'-C-methyl guanosine triphosphate; potent HCV replication inhibitor
6940 BTD Oct 2019
Selective TRPC5 activator
6573 Biotin-NAD+ Oct 2019
Biotinylated-NAD+; substrate for ADP-ribosylation
7006 PDD 00017272 Sep 2019
Potent PARG inhibitor
6427 Tafluprost Sep 2019
Very high affinity FP receptor agonist
7046 1,6-Hexanediol Sep 2019
Tool for probing liquid-liquid phase separation
7027 LY 2033298 Sep 2019
Selective positive allosteric modulator of M4 receptors; active in vivo; antipsychotic
7005 4-Thiouridine Sep 2019
Photoreactive uridine analog for RNA sequencing
6821 ZAP 180013 Sep 2019
Zap70 inhibitor; inhibits interaction with ITAMs
5847 ZLD 1039 Sep 2019
Potent and selective EZH2 inhibitor; orally bioavailable
6950 Thalidomide - linker 11 Sep 2019
Thalidomide-PEG3-ethylamine
6970 aTAG 2139 Sep 2019
Degrader of MTH1 fusion proteins for use within the aTAG system
6889 ML 418 Sep 2019
Kir 7.1 inhibitor; also inhibits Kir 6.2
6972 A 1899 Sep 2019
Potent K2P3.1 (TASK-1) and K2P9.1 (TASK-3) blocker
6797 KLD 12 Sep 2019
Self-assembling peptide; forms hydrogel to support cell growth
6764 B 973B Sep 2019
Positive allosteric modulator of α7 nAChRs; analgesic
6906 BAY 293 Negative Control Sep 2019
Negative control for BAY 293 (Cat. No. 6857)
6937 BSJ-04-132 Sep 2019
Selective Cdk4 degrader
6857 BAY 293 Sep 2019
Potent KRas/SOS1 interaction inhibitor
7020 LDV Sep 2019
α4β1 (VLA-4) ligand
6899 TH 257 Sep 2019
Potent and selective allosteric LIMK 1/2 inhibitor
6980 BAY 87-2243 Sep 2019
Mitochondrial complex I inhibitor
6888 ML 402 Sep 2019
Selective TREK channel activator
6893 VU 6005649 Sep 2019
Positive allosteric modulators of mGlu7 and mGlu8 receptors; also NK1 antagonist; brain penetrant
6803 MRK 740 Sep 2019
Potent PRDM9 inhibitor
6765 JTP 103237 Aug 2019
Potent and selective monoacyglycerol acyltransferase 2 (MOGAT2) inhibitor
6938 BSJ-03-204 Aug 2019
Selective Cdk4/6 degrader
6201 J 2156 Aug 2019
Selective high affinity human sst4 agonist
6927 Glucagon (Human, Porcine) Aug 2019
Endogenous glucagon receptor agonist
6921 BSJ-03-123 Aug 2019
Selective Cdk6 degrader
6994 HODHBt Aug 2019
STAT5-SUMO protein-protein interaction inhibitor
6978 AZD 5363 Aug 2019
Potent pan-AKT inhibitor
6859 FITM Aug 2019
Potent and selective negative allosteric modulator of mGlu1 receptors
6922 BSJ-Bump Aug 2019
Negative control for BSJ-03-123 (Cat. No. 6921)
6623 TFAX 546, SE Aug 2019
Yellow fluorescent dye; amine reactive
6930 Amphotericin B Aug 2019
Forms monovalent ion channels in lipid bilyers; antifungal
6619 TFAX 488, SE Aug 2019
Green fluorescent dye; amine reactive
5861 ARN 726 Aug 2019
Potent N-acylethanolamine acid amidase (NAAA) inhibitor; NAAA activity-based protein profiling (ABPP) probe
6109 Methylnaltrexone bromide Aug 2019
μ antagonist; peripherally restricted
6054 R162 Aug 2019
Glutamate dehydrogenase (GDH1) inhibitor
6823 CycLuc 1 Jul 2019
Synthetic luciferase substrate; brain penetrant; displays NIR emission
6776 G5 Jul 2019
Ubiquitin isopeptidase inhibitor; induces apoptosis
6751 (R)-(-)-Ketamine hydrochloride Jul 2019
NMDA antagonist; antidepressant; may not display psychotomimetic or addictive side effects of (S)-ketamine
6902 OLT 1177 Jul 2019
NLRP3 inflammasome inhibitor; disrupts inflammasome formation
6954 L-Buthionine sulfoximine Jul 2019
Irreversible γ-glutamylcysteine synthetase (γ-GCS) inhibitor; induces ferroptosis