New Products

View all new products by date added

Search for new products by date added, alphabetically, or by pharmacological action.

New products are an essential component of our range. Introductions are made on an ongoing basis, with hundreds of new small molecules and peptides being added every year. Our aim is to find the latest, otherwise unobtainable research tools, and bring them to the market as quickly as we can. New products can be identified throughout the Tocris website by the symbol.

If you can't find what you are looking for we welcome new product suggestions. If you would like to be kept informed about new products by email, please sign up for our monthly e-alert service.

Cat. No. 产品名称/活性 Date Added
7388 ND1-YL2 Feb 2021
SRC-1 peptide-based PROTAC®; active in vivo
7319 BRD PHOTAC-I-3 Feb 2021
Photoswitchable BET bromodomain degrader (PHOTAC)
7033 AY 77 Feb 2021
Potent PAR2 biased agonist; exhibits bias for Ca2+ signaling
7195 MCU i4 Feb 2021
Negative modulator of mitochondrial Ca2+ uniporter (MCU)
7217 VH 032 amide-alkylC5-acid Feb 2021
VHL ligand with alkyl linker and terminal acid for onward chemistry
6741 GW 4869 Feb 2021
Selective neutral sphingomyelin phosphodiesterase (N-SMase) inhibitor
7265 GMB 475 Feb 2021
BCR-ABL1 kinase PROTAC®
7366 WM 3835 Feb 2021
Lysine acetyltransferase HBO1 (KAT7) inhibitor
7034 AY 254 Feb 2021
Potent PAR2 biased agonist; exhibits bias for ERK1/2 signaling
6693 WM 8014 Feb 2021
Potent and selective KAT6A and KAT6B inhibitor
7256 ARV 771 Feb 2021
Potent BET bromodomain PROTAC®; also degrades BRD-tagged chimeric antigen receptors (CAR) in T cells
7273 C-Laurdan Jan 2021
Two-photon polarity-sensitive lipid membrane probe
7374 dTAGV-1 hydrochloride Jan 2021
Hydrochloride salt of dTAGV-1 (Cat. No. 6914); suitable for in vivo use
7175 DOPE Jan 2021
Liposome/lipoplex transfection enhancer
7282 Bortezomib Jan 2021
High affinity proteasome inhibitor
7268 SJFα Jan 2021
Potent and selective p38α PROTAC®
7192 SMIP 004 Jan 2021
SKP2 (S-phase kinase-associated protein 2) inhibitor; upregulates p27 and arrests cell cycle in G1 phase
7352 YM 254890 Jan 2021
Gα-protein inhibitor; potent inhibitor of Gq/11 signaling
6261 VCP 171 Jan 2021
Positive allosteric modulator (PAM) of A1 receptors; also allosteric partial agonist in absence of orthosteric agonist
7377 BIIE 0246 hydrochloride Dec 2020
Potent, selective and competitive non-peptide NPY Y2 receptor antagonist; active in vivo
7216 VH 032 amide-alkylC3-acid Dec 2020
VHL ligand with alkyl linker and terminal acid for onward chemistry
7267 SJFδ Dec 2020
Potent and selective p38δ PROTAC®
7266 SJF 8240 Dec 2020
c-MET PROTAC®; also degrades exon-14-deleted c-MET
7370 3-Aminotyrosine Dec 2020
Unnatural amino acid for inducing red shift in fluorescent proteins and fluorescent protein-based biosensors
7228 MPro 13b Dec 2020
Coronavirus Mpro inhibitor
7312 HM Janelia Fluor® 526, SE Dec 2020
Spontaneously blinking green-emitting dye for SMLSM; λabsλem 526/550 nm
7353 MSA 2 Dec 2020
Non-nucleotide STING agonist; orally bioavailable
7184 SGC 6870N Dec 2020
Negative control for SGC 6870 (Cat. No. 7182)
7182 SGC 6870 Dec 2020
Potent and selective PRMT6 inhibitor
6990 SET 2 Dec 2020
Selective TRPV2 antagonist
7322 SP 10 Dec 2020
Highly potent inhibitor of SARS-CoV Spike (S) protein and ACE2 interaction
7073 VH 032 amide-alkylC3-amine Dec 2020
VHL ligand with alkyl linker and terminal amine for onward chemistry
7338 K 22 Dec 2020
Inhibits coronavirus RNA replication; impairs double membrane vesicle (DMV) formation
7156 WQ 1 Dec 2020
Potent and selective σ1 receptor antagonist; active in vivo
7131 TM 38837 Dec 2020
Highly potent CB1 inverse agonist; peripherally restricted
6562 BAY 707 Dec 2020
Potent and selective MTH1 inhibitor
7105 VH 032 amide-PEG5-acid Nov 2020
VHL ligand with PEG linker and terminal acid for onward chemistry
7258 Gefitinib-based PROTAC® 3 Nov 2020
Potent EGFR PROTAC®
7255 ARCC 4 negative control Nov 2020
Negative control for ARCC 4 (Cat. No. 7254)
7303 iHAP1 Nov 2020
Allosteric activator of protein phosphatase 2A (PP2A)
7254 ARCC 4 Nov 2020
Potent and selective androgen receptor PROTAC®
7197 JHU 37152 Nov 2020
High affinity and highly potent hM3Dq and hM4Di DREADD agonist; blood brain barrier penetrant
7213 Pomalidomide 4'-PEG4-acid Nov 2020
Cereblon ligand with PEG linker and terminal acid for onward chemistry
7260 TBK1 control PROTAC® 4 Nov 2020
Negative control for TBK1 PROTAC® 3i (Cat. No. 7259)
7302 Sulfo-NHS-LC-Biotin Nov 2020
Amine reactive biotinylation reagent, cell impermeable
5927 NS 383 Nov 2020
ASIC blocker; active in vivo
7259 TBK1 PROTAC® 3i Nov 2020
Potent TANK-binding kinase 1 (TBK1) PROTAC®
7198 JHU 37160 Nov 2020
High affinity and highly potent hM3Dq and hM4Di DREADD agonist; blood brain barrier penetrant
6322 LW 6 Nov 2020
Malate dehydrogenase-2 (MDH2) inhibitor; also inhibits HIF-1α
7357 PLpro inhibitor 6 Oct 2020
SARS-CoV and SARS-CoV-2 PLpro inhibitor
7199 (±)-Eriodictyol Oct 2020
Potent TRPV1 antagonist; also antioxidant; activates Nrf2/ARE signaling
7294 VH 101 phenol-alkylC6-amine Oct 2020
VHL ligand with alkyl linker and terminal amine for onward chemistry
7059 GLPG 0187 Oct 2020
Potent αv integrin inhibitor
7193 Deschloroclozapine Oct 2020
High affinity and highly potent activator of hM3Dq and hM4Di DREADDs; rapidly blood brain barrier penetrant
7329 Thalidomide 4'-ether-alkylC2-acid Oct 2020
Cereblon ligand with alkyl linker and terminal acid for onward chemistry
7350 Tocriscreen Antiviral Library Oct 2020
Antiviral compound library for high throughput screening, chemical biology applications and drug repurposing; contains 240 bioactive compounds (100 μL 10 mM DMSO solutions)
7219 CRBN PROTAC® 14a Oct 2020
Cereblon Degrader (PROTAC®)
7188 Carfilzomib Oct 2020
Potent irreversible proteasome inhibitor; active in vivo
7106 VH 032 amide-alkylC2-acid Oct 2020
VHL ligand with alkyl linker and terminal acid for onward chemistry
7285 DCLK1-IN-1 Oct 2020
Potent and selective doublecortin like kinase 1/2 (DCLK1/2) inhibitor; orally bioavailable
7335 Thalidomide 4'-ether-alkylC8-acid Oct 2020
Cereblon ligand with alkyl linker and terminal acid for onward chemistry
7331 Thalidomide 4'-ether-alkylC4-acid Oct 2020
Cereblon ligand with alkyl linker and terminal acid for onward chemistry
7293 VH 101 phenol-alkylC4-amine Oct 2020
VHL ligand with alkyl linker and terminal amine for onward chemistry
5950 Ethyl LipotF Oct 2020
Selective FTO inhibitor
7143 VX 765 Oct 2020
High affinity and selective caspase-4 and caspase 1/ICE inhibitor; orally bioavailable
7330 Thalidomide 4'-ether-alkylC3-acid Sep 2020
Cereblon ligand with alkyl linker and terminal acid for onward chemistry
6996 BOP-JF549 Sep 2020
Yellow fluorescent dual α9β1/α4β1 integrin inhibitor comprising BOP conjugated to Janelia Fluor® 549; fluorogenic; photostable
7191 Santacruzamate A Sep 2020
Highly potent and selective HDAC2 inhibitor
7287 FAM-DEALA-Hyp-YIPD Sep 2020
Fluorescent HIF-1α peptide; can be used to evaluate the effect of VHL binding on degradation activity
7334 Thalidomide 4'-ether-alkylC7-acid Sep 2020
Cereblon ligand with alkyl linker and terminal acid for onward chemistry
7333 Thalidomide 4'-ether-alkylC6-acid Sep 2020
Cereblon ligand with alkyl linker and terminal acid for onward chemistry
7332 Thalidomide 4'-ether-alkylC5-acid Sep 2020
Cereblon ligand with alkyl linker and terminal acid for onward chemistry
7279 Janelia Fluor® 646, Tetrazine Sep 2020
Red dye (Reactive group: tetrazine). Applications: super-resolution microscopy e.g. dSTORM & STED, confocal and live cell imaging
7277 HBC 530 Sep 2020
GFP fluorophore mimic for imaging RNA in live cells; activated by binding to Pepper aptamers; suitable for confocal and two-photon microscopy
7104 VH 032 amide-PEG1-acid Sep 2020
VHL ligand with PEG linker and terminal acid for onward chemistry
7095 Pomalidomide 4'-PEG5-acid Sep 2020
Cereblon ligand with PEG linker and terminal acid for onward chemistry
7298 xStAx-VHLL Sep 2020
Selective peptide-based β-catenin Degrader (PROTAC®)
6238 PKRA 7 Sep 2020
Potent prokineticin (PK) 1 and 2 receptor antagonist; antitumor; BBB penetrant
7178 LCL 161, phenol Sep 2020
Functionalized IAP ligand for PROTACs
7262 SJF 1528 Sep 2020
Potent EGFR PROTAC®; also degrades HER2
7076 Lenalidomide 4'-PEG3-amine Sep 2020
Cereblon ligand with PEG linker and terminal amine for onward chemistry
7075 Lenalidomide 4'-PEG1-amine Sep 2020
Cereblon ligand with PEG linker and terminal amine for onward chemistry
6913 Thalidomide 4'-oxyacetamide-alkylC1-PEG3-alkylC3-amine Sep 2020
Cereblon ligand with alkyl-PEG-alkyl linker and terminal amine for onward chemistry
7288 Thalidomide-Cyanine 5 Sep 2020
Fluorescent cereblon probe
7159 FMF-04-159-R Sep 2020
Potent CDK14 and CDK16 inhibitor; displays reversible inhibition of CDK14
7158 FMF-04-159-2 Sep 2020
Potent covalent CDK14 and CDK16 inhibitor; also inhibits other TAIRE kinase family members
7261 SJF 1521 Sep 2020
Selective EGFR PROTAC®