New Products

View all new products by date added

Search for new products by date added, alphabetically, or by pharmacological action.

New products are an essential component of our range. Introductions are made on an ongoing basis, with hundreds of new small molecules and peptides being added every year. Our aim is to find the latest, otherwise unobtainable research tools, and bring them to the market as quickly as we can. New products can be identified throughout the Tocris website by the symbol.

If you can't find what you are looking for we welcome new product suggestions. If you would like to be kept informed about new products by email, please sign up for our monthly e-alert service.

Cat No Product Name / Activity Date Added
6589 (+)-JQ1 PA Sep 2018
'Click' target ligand for PROTACs; functionalized BET bromodomain inhibitor
6576 ABT 594 hydrochloride Sep 2018
Selective α4β2 nAChR agonist
6516 EPZ 015666 Sep 2018
Potent and selective PRMT5 inhibitor
6655 Amifostine Sep 2018
Cytoprotectant
6475 SU 6656 Sep 2018
Potent ATP-competitive Src family kinase inhibitor; also AMPK inhibitor; cell permeable
6602 1M7 Sep 2018
Reagent for RNA SHAPE-MaP chemistry
6531 NLS-StAx-h Sep 2018
Wnt inhibitor
5957 C3 Sep 2018
Selective microsomal prostaglandin E synthase 1 (mPGES-1) inhibitor
6067 M 30 dihydrochloride Sep 2018
Potent and non-selective MAO inhibitor; also an iron chelator and antioxidant
6126 KRH 3955 hydrochloride Sep 2018
Highly potent CXCR4 antagonist; inhibits HIV-1 replication
6508 GSK 1702934A Sep 2018
Potent and selective TRPC3/6 activator
6492 GSK'872 Sep 2018
Potent and selective receptor activating protein kinase 3 (RIP3) inhibitor
6257 OG 488, SE Sep 2018
Green fluorescent dye; supplied as NHS ester
6254 Flutax 2 Sep 2018
Green fluorescent taxol derivative
6255 Fluo-4 AM Sep 2018
Cell-permeable, fluorescent Ca2+ indicator
6648 NADA-green Sep 2018
Fluorescent D-amino acid for labeling peptidoglycans in live bacteria
6482 XMU MP 1 Sep 2018
Potent and selective MST1/2 inhibitor; orally bioavailable
6614 Jedi2 Sep 2018
Piezo1 channel activator
6349 Pelitinib Sep 2018
Potent irreversible EGFR inhibitor; orally bioavailable
4970 BMS 688521 Sep 2018
Potent inhibitor of the LFA-1/ICAM interaction
6557 Anti-human ErbB2 aptamer, Janelia Fluor® 646 conjugate Aug 2018
High affinity anti-human ErbB2 aptamer conjugated to Janelia Fluor® 646
6547 Ambuic Acid Aug 2018
Quorum sensing inhibitor; antibacterial
6528 SGC AAK1 1 Aug 2018
AAK1 and BMP2K inhibitor; activates Wnt signaling
6556 Anti-human EGFR aptamer, Janelia Fluor® 646 conjugate Aug 2018
High affinity anti-human EGFR aptamer conjugated to Janelia Fluor® 646
6367 Z 944 Aug 2018
Ca2+ channel blocker (T-type)
6632 ERGi-USU Aug 2018
Rio2 kinase (RIOK2) inhibitor; inhibits ERG protein
6532 THAL SNS 032 Aug 2018
Potent and selective CDK9 degrading PROTAC
6400 Alsterpaullone Aug 2018
Potent CDK1 and 2 inhibitor; also inhibits GSK-3β and Lck
6323 FX 1 Aug 2018
BCL6 inhibitor; 10-fold more potent than endogenous BCL6 corepressors
6583 UCLA GP130 2 Aug 2018
gp130 agonist; brain penetrant and neuroprotectant
6638 GSK 626616 Aug 2018
Potent and selective DYRK inhibitor; orally bioavailable.
6637 Pomalidomide - linker 1 Aug 2018
Pomalidomide-PEG2-ethylamine
6627 Thalidomide - linker 4 Aug 2018
Thalidomide-alkylC6-amine
6559 LY 450139 Aug 2018
γ-secretase pseudo-inhibitor
6269 JT010 Aug 2018
Potent and selective TRPA1 channel activator
6641 Roflumilast Aug 2018
Potent and selective PDE4 inhibitor
6229 LP 922761 Aug 2018
Potent AAK1 inhibitor; peripherally restricted
4690 Fmk Aug 2018
Irreversible ribosomal S6 kinase inhibitor 1/2 inhibitor
6539 Obatoclax mesylate Jul 2018
Inhibitor of Bcl-2 family members; antiapoptotic
6454 LY 2603618 Jul 2018
Potent and selective Chk1 inhibitor
6426 PSEM 89S Jul 2018
PSAML141F-GlyR and PSAML141F,Y115F-5-HT3 chimeric ion channel agonist
6555 TokeOni Jul 2018
NIR-emission luciferin analog; orally bioavailable and brain penetrant
6524 TL 12-186 Jul 2018
Multikinase degrading PROTAC
6425 PSEM 308 hydrochloride Jul 2018
PSAML141F-GlyR and PSAML141F,Y115F-5-HT3 chimeric ion channel agonist
6428 Carboprost tromethamine Jul 2018
Synthetic Prostaglandin F (Cat. No. 4214) analog
6422 DREADD agonist 21 dihydrochloride Jul 2018
Potent muscarinic DREADD agonist; water soluble version of DREADD agonist 21 (Cat. No. 5548)
6628 TC E3 5032 Jul 2018
Precursor to Pomalidomide-based PROTACs
6525 TL 13-27 Jul 2018
Negative control for TL 12-186
6330 AZ 5704 Jul 2018
Potent and selective ATM kinase inhibitor; orally bioavailable
TB2634-GMP DAPT Jul 2018
DAPT synthesized to cGMP guidelines
TB1614-GMP SB 431542 Jul 2018
SB 431542 synthesized to cGMP guidelines
6545 OB-1 Jul 2018
Stomatin-like protein-3 (STOML3) oligomerization inhibitor
6483 Isoginkgetin Jul 2018
Pre-mRNA splicing inhibitor; cell permeable
5910 TL4-12 Jul 2018
Potent MAP4K2 (GCK) inhibitor
6153 JQEZ5 Jul 2018
Potent and selective SAM-competitive EZH2 inhibitor
4007 Laulimalide Jul 2018
Microtubule stabilzing agent
6520 Abiraterone acetate Jul 2018
Potent CYP17A1 inhibitor
6491 YM 155 Jul 2018
Survivin suppressor
6486 Aprepitant Jul 2018
Potent long-acting hNK-1 antagonist
6479 CU CPT 9a Jul 2018
Potent TLR8 inhibitor
6542 Ivabradine hydrochloride Jul 2018
HCN channel blocker; inhibits If pacemaker current
6517 Liraglutide Jul 2018
Highly potent, long-acting GLP-1 receptor agonist
6476 Compound E Jul 2018
γ-secretase inhibitor; induces neuronal differentiation
6199 BAY 876 Jul 2018
Potent and selective GLUT1 inhibitor
6538 PF 04449913 maleate Jul 2018
Potent Smo antagonist
6506 PF 06551600 malonate Jul 2018
Potent and selective JAK3 inhibitor
6480 GSK 583 Jul 2018
Potent RIP2 kinase inhibitor; orally bioavailable and cell permeable
6436 CY 09 Jul 2018
NLRP3 inhibitor; active in vivo
6578 GT 949 Jul 2018
Potent and selective positive allosteric modulator of EAAT2
6544 CID 1375606 Jul 2018
GPR27 agonist
6324 Autophinib Jul 2018
Potent VPS34 inhibitor
6281 SLM 6031434 hydrochloride Jul 2018
Selective sphingosine kinase 2 (Sphk2) inhibitor
6273 CRT 0105950 Jul 2018
Potent LIMK1/2 inhibitor
5767 SR 3029 Jul 2018
Potent and selective CK1δ and CK1ε inhibitor
6564 SGC GAK 1 Jul 2018
High affinity cyclin G associated kinase (GAK) inhibitor
6558 CP 43 Jul 2018
Potent TAOK inhibitor
6320 ESI 05 Jul 2018
EPAC2 inhibitor
6040 BRD 9757 Jul 2018
Potent and selective HDAC6 inhibitor
6179 UK 59811 hydrochloride Jul 2018
CaVAb blocker
6239 SAK 3 Jul 2018
Potent CaV3.1/3.3 activator; orally bioavailable
6554 (+)-Abscisic Acid Jun 2018
Endogenous LANCL2 agonist
6505 Avasimibe Jun 2018
ACAT inhibitor
6448 ML 351 Jun 2018
Selective 12/15 LOX inhibitor; active in vivo
6144 CX08005 Jun 2018
Competitive PTP1B inhibitor
5828 Ambrisentan Jun 2018
Selective ETA antagonist
6079 TC KHNS 11 Jun 2018
Potent and selective PI 3-kinase δ inhibitor; orally bioavailable
6037 LM22B 10 Jun 2018
TrkB and TrkC agonist; brain penetrant
6406 Hydroxystilbamidine bis(methanesulfonate) Jun 2018
Fluorescent cationic dye; neuronal tracer
6549 cAC 253 Jun 2018
Amylin (AMY3) receptor antagonist; brain penetrant
6296 Janelia Fluor® 525, SE Jun 2018
Cell permeable yellow fluorescent dye; supplied as NHS ester
6572 Biotin-LC-NAD+ Jun 2018
Biotinylated analog of β-NAD+. Commonly used reagent in LSD1 and PARP1 assays
6571 Biotin-11-dUTP Jun 2018
Biotin-labeled dUTP
6551 PAMP-12 (human, porcine) Jun 2018
Potent MRGPRX2 agonist
6113 Liproxstatin-1 hydrochloride Jun 2018
Potent ferroptosis inhibitor
6552 PAMP-20 (human) Jun 2018
MRGPRX2 agonist
6550 AC 253 May 2018
Amylin (AMY3) receptor antagonist
6244 OG-L002 May 2018
Potent LSD1 inhibitor
6017 THPN May 2018
Nur77 agonist; induces autophagy in melanoma cell lines
6548 N-(3-Oxododecanoyl)-L-homoserine lactone May 2018
Bacterial quorum sensing autoinducer; immunomodulator
6484 Terbinafine hydrochloride May 2018
Selective TASK3 activator; also inhibits fungal squalene epoxidase
6507 Saxagliptin hydrochloride May 2018
High affinity DPP-IV inhibitor; active in vivo
6383 SR 16832 May 2018
Dual site PPARγ inhibitor
3036 Loxiglumide May 2018
CCK1 antagonist; active in vivo
6223 XY 018 May 2018
RORγ antagonist; inhibits AR expression
6387 A 485 May 2018
Potent and selective p300/CBP inhibitor; orally bioavailable
6440 PIK 93 May 2018
Potent PI 3-Kγ, PI 3-Kα and PI 4-KIIIβ inhibitor
6166 AMG 18 hydrochloride May 2018
Potent and selective IRE1α inhibitor
6139 NS 6740 May 2018
High affinity α7 nAChR partial agonist; anti-inflammatory
6469 Thalidomide - linker 3 Apr 2018
Thalidomide-alkylC4-amine
6463 VH 032 - linker 1 Apr 2018
VH 032-PEG3-amine
6468 Thalidomide - linker 2 Apr 2018
Thalidomide-PEG4-ethylamine
6465 VH 032 - linker 3 Apr 2018
VH 032-alkylC4-amine
6455 Tocriscreen Plus Micro Apr 2018
A library of 1280 biologically active compounds (15 μL 10 mM DMSO solutions)
6438 BRD 6989 Apr 2018
Cdk8 inhibitor; enhances IL-10 production
6467 Thalidomide - linker 1 Apr 2018
Thalidomide-PEG3-ethylamine
6464 VH 032 - linker 2 Apr 2018
VH 032-PEG4-amine
6494 Galangin Apr 2018
TRPC5 inhibitor; also induces autophagy
6417 CMP 98 Apr 2018
Negative Control for CM 11
6416 CM 11 Apr 2018
Homo-PROTAC for self-degradation of pVHL30
6515 (D)-PPA 1 Apr 2018
PD-1/PD-L1 interaction inhibitor
6409 A 1210477 Apr 2018
Selective, high affinity Mcl-1 inhibitor; proapoptotic
4647 GR 203040 Apr 2018
Potent and selective NK1 antagonist
3649 CP 122721 hydrochloride Apr 2018
High affinity NK1 antagonist
6392 B02 Apr 2018
RAD51 recombinase inhibitor
6435 ML 323 Apr 2018
Potent and selective USP1-UAF1 allosteric inhibitor
5730 A 127722 Mar 2018
Highly potent, selective ETA antagonist; orally bioavailable