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Biological Activity for NIKi
NIKi is a potent inhibitor of NF-κB-inducing kinase (NIK) activity (IC50 = 20 nM).
Technical Data for NIKi
|Storage||Store at -20°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Solubility Data for NIKi
|Solvent||Max Conc. mg/mL||Max Conc. mM|
Preparing Stock Solutions for NIKi
The following data is based on the product molecular weight 366.42. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||2.73 mL||13.65 mL||27.29 mL|
|5 mM||0.55 mL||2.73 mL||5.46 mL|
|10 mM||0.27 mL||1.36 mL||2.73 mL|
|50 mM||0.05 mL||0.27 mL||0.55 mL|
References for NIKi
References are publications that support the biological activity of the product.
Li et al (2013) Inhibiting NF-κB-inducing kinase (NIK): discovery, structure-based design, synthesis, structure-activity relationship, and co-crystal structures. Bioorg.Med.Chem.Lett. 23 1238 PMID: 23374866
If you know of a relevant reference for NIKi, please let us know.
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Citations for NIKi
Citations are publications that use Tocris products.
Currently there are no citations for NIKi. Do you know of a great paper that uses NIKi from Tocris? Please let us know.
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Literature in this Area
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