Nrf2 Activators

Cat. No. Product Name / Activity
5145 AI-3
ARE activator; induces Nrf2-ARE-dependent transcription
4626 Andrographolide
Inhibits NFκB; activates Nrf2
4737 CDDO Im
Nrf2 signaling activator
6646 CDDO-Me
Nrf2 pathway activator; also NF-κB pathway inhibitor; inhibits IKKβ
2841 Curcumin
Antitumor and anti-inflammatory; activates Nrf2
4512 DMF
Activator of Nrf2 pathway; neuroprotective
6172 INF 4E
Activates Keap1-Nrf2 pathway; also caspase-1 and NLRP3 inflammasome inhibitor
5625 ML 334
Inhibitor of Keap1- Nrf2 interaction
4511 MMF
Activator of Nrf2 pathway; primary metabolite of DMF (Cat. No. 4512)
5293 NK 252
Nrf2 activator
6662 4-Octyl itaconate
Nrf2 activator; cell permeable
5294 Oltipraz
Nrf2 activator
5707 RA 839
Nrf2 activator; inhibits Nrf2/Keap1 interaction
4811 TAT 14
Nrf2 pathway activator; blocks Nrf2/Keap1 interaction

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