You can now submit reviews for your favorite Tocris products. Your review will help other researchers decide on the best products for their research. Why not submit a review today?!Submit Review
Biological Activity for 4-Octyl itaconate
4-Octyl itaconate is an activates Nrf2. Inhibits LPS-induced increases in IL-1β mRNA, HIF-1α and IL-10 in macrophages. Decreases cytokine production in response to LPS in mice and prolongs survival. Cell permeable.
Compound Libraries for 4-Octyl itaconate
Technical Data for 4-Octyl itaconate
|Storage||Store at -20°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Solubility Data for 4-Octyl itaconate
|Solvent||Max Conc. mg/mL||Max Conc. mM|
Preparing Stock Solutions for 4-Octyl itaconate
The following data is based on the product molecular weight 242.31. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||4.13 mL||20.63 mL||41.27 mL|
|5 mM||0.83 mL||4.13 mL||8.25 mL|
|10 mM||0.41 mL||2.06 mL||4.13 mL|
|50 mM||0.08 mL||0.41 mL||0.83 mL|
Product Datasheets for 4-Octyl itaconate
References for 4-Octyl itaconate
References are publications that support the biological activity of the product.
Mills et al (2018) Itaconate is an anti-inflammatory metabolite that activates Nrf2 via alkylation of KEAP1. Nature 556 113 PMID: 29590092
If you know of a relevant reference for 4-Octyl itaconate, please let us know.
View Related Products by Product Action
Keywords: 4-Octyl itaconate, 4-Octyl itaconate supplier, anti-inflammatory, Nrf2, activators, activates, cell, permeable, 6662, Tocris Bioscience
Citations for 4-Octyl itaconate
Citations are publications that use Tocris products.
Currently there are no citations for 4-Octyl itaconate. Do you know of a great paper that uses 4-Octyl itaconate from Tocris? Please let us know.
Reviews for 4-Octyl itaconate
There are currently no reviews for this product. Be the first to review 4-Octyl itaconate and earn rewards!
Have you used 4-Octyl itaconate?
Submit a review and receive an Amazon gift card.
$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image
$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image
Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.