You can now submit reviews for your favorite Tocris products. Your review will help other researchers decide on the best products for their research. Why not submit a review today?!Submit Review
Biological Activity for NK 252
NK 252 is an Nrf2 activator; interacts with the Nrf2-binding site of Keap1. Downregulates the expression of fibrogenic genes and increases antioxidant effects in NASH rat models of liver disease.
Compound Libraries for NK 252
Technical Data for NK 252
|Storage||Store at +4°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Solubility Data for NK 252
|Solvent||Max Conc. mg/mL||Max Conc. mM|
Preparing Stock Solutions for NK 252
The following data is based on the product molecular weight 285.26. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||3.51 mL||17.53 mL||35.06 mL|
|5 mM||0.7 mL||3.51 mL||7.01 mL|
|10 mM||0.35 mL||1.75 mL||3.51 mL|
|50 mM||0.07 mL||0.35 mL||0.7 mL|
References for NK 252
References are publications that support the biological activity of the product.
Shimozono et al (2013) Nrf2 activators attenuate the progression of nonalcoholic steatohepatitis-related fibrosis in a dietary rat model. Mol.Pharmacol. 84 62 PMID: 23592516
If you know of a relevant reference for NK 252, please let us know.
View Related Products by Product Action
Keywords: NK 252, NK 252 supplier, NK252, NRF2, activators, activates, Keap1, Nrf2, 5293, Tocris Bioscience
Citations for NK 252
Citations are publications that use Tocris products.
Currently there are no citations for NK 252. Do you know of a great paper that uses NK 252 from Tocris? Please let us know.
Reviews for NK 252
There are currently no reviews for this product. Be the first to review NK 252 and earn rewards!
Have you used NK 252?
Submit a review and receive an Amazon gift card.
$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image
$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image
Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.