New Product: dTAGV-1 is an exciting addition to our TAG Degradation product range for Targeted Protein Degradation and target validation. The product recruits the E3 ligase VHL, offering an alternative to our existing tools in the range, which harness CRBN.
MPro 13b is a new small molecule coronavirus MPro inhibitor with activity at MERS-CoV, SARS-CoV and SARS-CoV-2 main protease. MPro 13b inhibits SARS-CoV-2 infection of human cells in vitro.
Deschloroclozapine (DCZ) is a highly potent hM3Dq and hM4Di DREADD agonist. This DREADD ligand displays superior specificity and blood brain barrier penetration making it an excellent option for in vivo electrophysiology experiments.