Phosphodiesterase Inhibitor Tocriset™

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Contents of Tocriset:

Cat.No. Product Name / Activity
0415Ro 20-1724
widely used PDE inhibitor, selective for PDE4
0915Cilostamide
selective inhibitor of PDE3
1046Zardaverine
selective inhibitor of PDE3 and 4
1349(R)-(-)-Rolipram
selective inhibitor of PDE4
1504Milrinone
potent inhibitor of PDE3
Description: Selection of 5 phosphodiesterase inhibitors (Cat. Nos. 0915, 1504, 0415, 1349 and 1046)
Datasheet
Citations
Literature

Biological Activity

Contains the listed products which can be used to investigate signalling pathways involving PDE3 and PDE4. The products are pre-dissolved in DMSO at a stock concentration of 10 mM in 0.5 ml.

Technical Data

Tocrisets contain 3-5 ligands supplied as lyophilized solids or pre-dissolved in DMSO at a specified concentration. Lyophilized solids have been freeze-dried (approximately 0.5-2 mg per vial) so that addition of 0.5 or 1 ml of solvent produces a stock concentration of 10 or 5 mM respectively.

Please see individual product listings for specific technical data and certificate of analysis.

Technical Data

Storage Store at -20°C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Product Datasheets

Certificate of Analysis / Product Datasheet
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Safety Datasheet

References

References are publications that support the products' biological activity.

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Citations for Phosphodiesterase Inhibitor Tocriset™

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Literature in this Area

Cancer

Cancer Research Product Guide

A collection of over 750 products for cancer research, the guide includes research tools for the study of:

  • Cancer Metabolism
  • Epigenetics in Cancer
  • Receptor Signaling
  • Cell Cycle and DNA Damage Repair
  • Angiogenesis
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