Lithium carbonate

Discontinued Product

Lithium carbonate (Cat. No. 4740) has been withdrawn from sale for commercial reasons.
Description: Mood stabilizer; inhibits GSK-3 in vivo
Chemical Name: Carbonic acid dilithium salt
Citations (1)
Reviews (1)
Literature (4)
Pathways (1)

Biological Activity for Lithium carbonate

Lithium carbonate is a mood stabilizer; thought to act by reducing catecholamine neurotransmitter concentration, through an effect on the Na+/K+ ATPase pump. Effective in the treatment of bipolar disorder. Inhibits GSK-3 in vivo.

Technical Data for Lithium carbonate

M. Wt 73.89
Formula Li2CO3
Storage Store at RT
CAS Number 554-13-2
PubChem ID 11125
Smiles [Li+].[Li+].[O-]C([O-])=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets for Lithium carbonate

References for Lithium carbonate

References are publications that support the biological activity of the product.

Lenox and Hahn (2000) Overview of the mechanism of action of Li in the brain: fifty-year update. J.Clin.Psychiatry 61 5 PMID: 10826655

Gould et al (2004) In vivo evidence in the brain for Li inhibition of glycogen synthase kinase-3. Neuropsychopharmacology 29 32 PMID: 12942141

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Keywords: Lithium carbonate, Lithium carbonate supplier, Mood, stabilizers, sodium, potassium, Na+/K+, ATPase, pumps, bipolar, Glycogen, Synthase, Kinase, 3, 4740, Tocris Bioscience

⚠ WARNING: This product can expose you to chemicals including Lithium carbonate, which is known to the State of California to cause reproductive toxicity with developmental effects. For more information, go to

1 Citation for Lithium carbonate

Citations are publications that use Tocris products. Selected citations for Lithium carbonate include:

Irene et al (2018) Automatic quantification of juvenile zebrafish aggression. J Neurosci Methods 296 23-31 PMID: 29274793

Reviews for Lithium carbonate

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Li2CO3 prolongs cardiac action potential duration.
By Chintan Koyani on 10/23/2018
Assay Type: In Vitro
Species: Other
Cell Line/Tissue: Ventricular cardiomyocytes

Guinea pig ventricular cardiomyocytes were patched and stimulated at a 1 Hz frequency to record action potentials before and after Li2CO3 (10 and 30 µM). Li2CO3 significantly prolonged action potential duration at 20% and 90% repolarization levels.

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Literature in this Area

Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!

*Please note that Tocris will only send literature to established scientific business / institute addresses.

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Pathways for Lithium carbonate

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