Bromodomain (BRD) Degraders

Cat. No.	Product Name / Activity
Degraders
7256	ARV 771
	Potent BET bromodomain PROTAC^®; also degrades BRD-tagged chimeric antigen receptors (CAR) in T cells
6356	AT 1
	(+)-JQ1 based PROTAC^® with selectivity for BRD4
6327	dBET1
	(+)-JQ1 based Degrader (PROTAC^®) targeting BET bromodomains, active in vivo
6945	dBET6
	Potent and selective (+)-JQ1 based Degrader (PROTAC^®) targeting BET bromodomains, active in vivo
6606	dBRD9
	Potent and selective BRD9 Degrader (PROTAC^®)
6943	dBRD9-A
	Potent BRD9 Degrader (PROTAC^®)
7828	HHP 9
	BET bromodomain Degrader (PROTAC^®); also potent Hedgehog pathway inhibitor
8152	JQ dS-4
	BRG1/SMARCA4 Degrader (PROTAC^®)
6154	MZ 1
	(+)-JQ1 based Degrader (PROTAC^®) that preferentially degrades BRD4
7432	SIM1
	Potent and selective trivalent BET Bromodomain Degrader (PROTAC^®)
6936	VZ 185
	Potent and selective BRD7/9 Degrader (PROTAC^®)

8974 | SALAD1
Ultrabright fluorogenic dye for imaging RNA in live-cells

8865 | LTGO-33
Potent and selective state-independent inhibitor of NaV1.8 sodium channels

9026 | LipoLIVE™ Green Non-Toxic Dye
Ready-to-use fluorescent probe for the real-time visualization of lipid droplet dynamics in living cells

8994 | Biotin-PEG4-Diazirine
Photo-crosslinking capture probe for deazaflavin-diazirine energy-transfer labelling with a biotin handle

8135 | PIPE 3297 dihydrochloride
Potent and selective κ opioid receptor agonist; devoid of β-Arrestin-2 recruitment.

Literature in this Area

Targeted Protein Degradation and Induced Proximity Guide

This brochure highlights the products and services available from Bio-Techne to support Targeted Protein Degradation and Induced Proximity research.

A Chemical Toolbox to Support PROTAC R&D

This poster discusses the generation of a toolbox of building blocks for the development of Degraders.