Smoothened Receptor Antagonists

Cat. No.	Product Name / Activity
1623	Cyclopamine
	Inhibitor of Hedgehog (Hh) signaling; Smo antagonist
5554	IHR 1
	Potent Smo antagonist
5561	IHR-Cy3
	Potent fluorescent Smo antagonist
5981	Itraconazole
	SMO antagonist; acts at different binding site to cyclopamine (Cat No. 1623)
4717	Jervine
	Inhibitor of Hedgehog (Hh) signaling; binds directly to Smo
4917	M 25
	Potent Smoothened (Smo) receptor antagonist
4585	MRT 10
	Smoothened (Smo) antagonist
6538	PF 04449913 maleate
	Potent Smo antagonist
5262	PF 5274857 hydrochloride
	High affinity and selective Smoothened (Smo) receptor antagonist
1974	SANT-1
	Inhibitor of Hedgehog (Hh) signaling; antagonizes smoothened activity
3617	SANT-2
	Inhibitor of Hedgehog (Hh) signaling; antagonizes smoothened activity