Smoothened Receptor Antagonists

Cat. No. Product Name / Activity
1623 Cyclopamine
Inhibitor of Hedgehog (Hh) signaling; Smo antagonist
5554 IHR 1
Potent Smo antagonist
5561 IHR-Cy3
Potent fluorescent Smo antagonist
5981 Itraconazole
SMO antagonist; acts at different binding site to cyclopamine (Cat No. 1623)
4717 Jervine
Inhibitor of Hedgehog (Hh) signaling; binds directly to Smo
4917 M 25
Potent Smoothened (Smo) receptor antagonist
4585 MRT 10
Smoothened (Smo) antagonist
6538 PF 04449913 maleate
Potent Smo antagonist
5262 PF 5274857 hydrochloride
High affinity and selective Smoothened (Smo) receptor antagonist
1974 SANT-1
Inhibitor of Hedgehog (Hh) signaling; antagonizes smoothened activity
3617 SANT-2
Inhibitor of Hedgehog (Hh) signaling; antagonizes smoothened activity

Related Targets