Smoothened Receptor Antagonists

Cat. No. Product Name / Activity
1623 Cyclopamine
Inhibitor of Hedgehog (Hh) signaling; Smo antagonist
5554 IHR 1
Potent Smo antagonist
5981 Itraconazole
SMO antagonist; acts at different binding site to cyclopamine (Cat No. 1623)
6538 PF 04449913 maleate
Potent Smo antagonist
5262 PF 5274857 hydrochloride
High affinity and selective Smoothened (Smo) receptor antagonist
1974 SANT-1
Inhibitor of Hedgehog (Hh) signaling; antagonizes smoothened activity
7826 Sonidegib
Potent Smoothened receptor antagonist

Related Targets