Parathyroid Hormone Receptors

Parathyroid hormone (PTH) receptors are a group of Gs-protein-coupled receptors, currently divided into two subtypes: PTH1 and PTH2. Each subtype has a distinct distribution and mediates different biological actions. PTH1 is ubiquitously expressed.

Products
Background
Literature
Gene Data

Agonists

Cat No Product Name / Activity
5487 DPC AJ1951
Potent parathyroid hormone (PTH) receptor agonist
6303 Parathyroid hormone (1-34) (bovine)
Parathyroid hormone (PTH) receptor agonist.
6301 Parathyroid hormone (1-34) (rat)
Parathyroid hormone (PTH) receptor agonist
3011 Parathyroid hormone (1-34) (human)
Parathyroid hormone (PTH) receptor agonist

Parathyroid hormone (PTH) receptors are a group of Gs-protein-coupled receptors, currently divided into two subtypes: PTH1 and PTH2. Each subtype has a distinct distribution and mediates different biological actions. PTH1 is ubiquitously expressed, but is found at particularly high levels in skeletal muscle and the kidneys.

PTH1 is involved in calcium and phosphate homeostasis and has a role in chondrocyte regulation. PTH2 expression is limited to the brain and testes. Its actions are proposed to include nociception and regulation of pituitary hormone secretion. The human genes encoding the PTH1 and PTH2 receptors are located on chromosomes 3p22-21.1 and 2q33 respectively.

External sources of pharmacological information for Parathyroid Hormone Receptors :

Literature for Parathyroid Hormone Receptors

GPCR

GPCR Product Listing

A collection of over 450 products for G protein-coupled receptors, the listing includes research tools for the study of:

  • Rhodopsin-like Receptors
  • Secretin-like Receptors
  • Glutamate Receptors
  • Frizzled Receptors
  • GPCR Signaling
Peptide Hormone Receptors

Peptide Hormone Receptors Product Listing

A collection of over 200 products for peptide hormone receptors, the listing includes research tools for the study of:

  • Anterior Pituitary Regulation
  • Blood Pressure Regulation
  • Feeding and Appetite Regulation
  • Glucose Regulation
  • Peptide Hormone Processing

Parathyroid Hormone Receptor Gene Data

Gene Species Gene Symbol Gene Accession No. Protein Accession No.
PTH1 Human PTH1R NM_000316 Q03431
Mouse Pth1r NM_001083936 P41593
Rat Pth1r NM_011199 P41593
PTH2 Human PTH2R NM_005048 P49190
Mouse Pth2r NM_139270 Q91V95
Rat Pthr2 NM_031089 P70555