Parathyroid Hormone Receptors

Parathyroid hormone (PTH) receptors are a group of G_s-protein-coupled receptors, currently divided into two subtypes: PTH₁ and PTH₂. Each subtype has a distinct distribution and mediates different biological actions. PTH₁ is ubiquitously expressed, but is found at particularly high levels in skeletal muscle and the kidneys.

PTH₁ is involved in calcium and phosphate homeostasis and has a role in chondrocyte regulation. PTH₂ expression is limited to the brain and testes. Its actions are proposed to include nociception and regulation of pituitary hormone secretion. The human genes encoding the PTH₁ and PTH₂ receptors are located on chromosomes 3p22-21.1 and 2q33 respectively.

External sources of pharmacological information for Parathyroid Hormone Receptors :

• IUPHAR Receptor Code

• BJP Guide

Literature for Parathyroid Hormone Receptors

Tocris offers the following scientific literature for Parathyroid Hormone Receptors to showcase our products. We invite you to request* your copy today!

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GPCR Product Listing

A collection of over 450 products for G protein-coupled receptors, the listing includes research tools for the study of:

• Rhodopsin-like Receptors
• Glutamate Receptors
• Frizzled Receptors
• GPCR Signaling

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Peptide Hormone Receptors Product Listing

A collection of over 200 products for peptide hormone receptors, the listing includes research tools for the study of:

• Anterior Pituitary Regulation
• Blood Pressure Regulation
• Feeding and Appetite Regulation
• Glucose Regulation
• Peptide Hormone Processing

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Parathyroid Hormone Receptor Gene Data