Adenosine A3 Receptors
The adenosine A3 receptor is a member of the adenosine receptor group of G-protein-coupled receptors that also includes A1, A2A and A2B. They display high expression levels in the testes and mast cells of rats, with low expression levels in the thyroid, liver, kidney and heart.
Adenosine A3 Receptor Agonists |
|
|---|---|
| Cat. No. | Product Name / Activity |
| 1104 | 2-Cl-IB-MECA |
| Highly selective A3 agonist | |
| 1579 | HEMADO |
| High affinity selective A3 agonist | |
| 1066 | IB-MECA |
| A3 selective agonist | |
| 5428 | MRS 5698 |
| High affinity and selective A3 agonist | |
Adenosine A3 Receptor Antagonists |
|
| Cat. No. | Product Name / Activity |
| 4041 | MRE 3008F20 |
| Highly potent and selective adenosine A3 receptor antagonist | |
| 1217 | MRS 1220 |
| Highly potent and selective hA3 antagonist | |
| 1385 | MRS 1334 |
| Potent, highly selective hA3 antagonist | |
| 2010 | PSB 10 hydrochloride |
| Potent, highly selective hA3 receptor antagonist/inverse agonist | |
The adenosine A3 receptor is a member of the adenosine receptor group of G-protein-coupled receptors that also includes A1, A2A and A2B. They display high expression levels in the testes and mast cells of rats, with low expression levels in the thyroid, liver, kidney, heart, intestine and most brain areas. Adenosine A3 receptors play a role in mast cell degranulation, coronary vasodilation and protection from reperfusion. The human A3 receptor gene is localized on chromosome 1 (1p21-p13).
External sources of pharmacological information for Adenosine A3 Receptors :
Literature for Adenosine A3 Receptors
Tocris offers the following scientific literature for Adenosine A3 Receptors to showcase our products. We invite you to request* your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.
Cardiovascular Research Product Guide
A collection of over 250 products for cardiovascular research, the guide includes research tools for the study of:
- Hypertension
- Thrombosis and Hemostasis
- Atherosclerosis
- Myocardial Infarction
- Ischemia/Reperfusion Injury
- Arrhythmias
- Heart Failure
GPCR Product Listing
A collection of over 450 products for G protein-coupled receptors, the listing includes research tools for the study of:
- Rhodopsin-like Receptors
- Glutamate Receptors
- Frizzled Receptors
- GPCR Signaling
Pain Research Product Guide
A collection of over 280 products for pain research, the guide includes research tools for the study of:
- Nociception
- Ion Channels
- G-Protein-Coupled Receptors
- Intracellular Signaling
Cardiovascular Poster
Cardiovascular disease remains one of the major causes of morbidity and mortality in the Western world and therefore this therapeutic area continues to be of great interest to researchers. This poster highlights the key GPCRs regulating vascular reactivity.
Our Cardiovascular Guide highlights over 250 products for cardiovascular research.
Request copyRequest PDF
Our Pain guide highlights over 280 products for Pain research.
Request copyRequest PDFWritten by J.J. Maguire and A.P. Davenport
Our Cardiovascular poster highlights the key G protein-coupled receptors involved in the regulation of vascular reactivity.
Request copyDownload PDF