Home / Product Type / Reagents / ROS and Other Gaseous Donors / CORM 2

CORM 2

Cat. No. 6117 Submit a Review Datasheet / COA / SDS
Pricing Availability   Qty
Cat.No. 6117 - CORM 2 | C6Cl4O6Ru2 | CAS No. 22594-69-0
Description: Carbon monoxide-releasing molecule
Chemical Name: Tricarbonyldichlororuthenium(II) dimer
Datasheet
Citations
Reviews
Biological Activity Technical Data Solubility Calculators Datasheets References

Biological Activity

Carbon monoxide-releasing molecule. Causes vasodilatation in isolated aortic rings in vitro. Cytotoxic to smooth muscle cells in vitro after prolonged (24h) exposure. Exhibits antihypertensive effects in vivo. Reduces tight-junction disruption in intestinal mucosa in a rat sepsis model.

Technical Data

M. Wt 512.01
Formula C6Cl4O6Ru2
Storage Store at RT
CAS Number 22594-69-0
PubChem ID 10951331
InChI Key JYHHJVKGDCZCCL-UHFFFAOYSA-J
Smiles [Cl-][Ru++]1([Cl-][Ru++]([Cl-])([Cl-]1)(C#[O])(C#[O])C#[O])(C#[O])(C#[O])C#[O]

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility Data

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 51.2 100

Preparing Stock Solutions

The following data is based on the product molecular weight 512.01. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.95 mL 9.77 mL 19.53 mL
5 mM 0.39 mL 1.95 mL 3.91 mL
10 mM 0.2 mL 0.98 mL 1.95 mL
50 mM 0.04 mL 0.2 mL 0.39 mL

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.
=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Dilution Calculator

Calculate the dilution required to prepare a stock solution.
x
=
x

References

References are publications that support the biological activity of the product.

Zhang et al (2015) Carbon monoxide-releasing molecule-2 reduces intestinal epithelial tight-junction damage and mortality in septic rats. PLoS One 10 e0145988 PMID: 26720630

Motterlini et al (2002) Carbon monoxide-releasing molecules: characterization of biochemical and vascular activities. Circ.Res. 90 E17 PMID: 11834719

If you know of a relevant reference for CORM 2, please let us know.

View Related Products by Target

Keywords: CORM 2, CORM 2 supplier, CORM2, CO, carbon, monoxide, releasing, moleculea, antihypertensives, vasorelaxant, ROS, Donors, Miscellaneous, Compounds, 6117, Tocris Bioscience

Citations for CORM 2

Citations are publications that use Tocris products.

Currently there are no citations for CORM 2. Do you know of a great paper that uses CORM 2 from Tocris? Please let us know.

Reviews for CORM 2

There are currently no reviews for this product. Be the first to review CORM 2 and earn rewards!

Have you used CORM 2?

Submit a review and receive an Amazon gift card.

$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image

$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review