Amifostine

Discontinued Product

Amifostine (Cat. No. 6655) has been withdrawn from sale for commercial reasons.
Description: Cytoprotectant
Chemical Name: 2-[(3-Aminopropyl)amino]ethanethiol dihydrogen phosphate
Datasheet
Citations
Reviews

Biological Activity for Amifostine

Amifostine is a cytoprotectant against chemotherapy and radiotherapy. Reduces mitochondrial pyruvate use in hepatocytes but not hepatoma cells in vitro. Also inhibits angiogenesis.

Active metabolite is also available, WR 1065 (Cat. No. 3356)

Technical Data for Amifostine

M. Wt 214.22
Formula C5H15N2O3PS
Storage Store at +4°C
CAS Number 20537-88-6
PubChem ID 2141
InChI Key JKOQGQFVAUAYPM-UHFFFAOYSA-N
Smiles NCCCNCCSP(O)(O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets for Amifostine

Certificate of Analysis / Product Datasheet
Select another batch:

References for Amifostine

References are publications that support the biological activity of the product.

Giannopoulou et al (2003) AmiF. inhibits angiogenesis in vivo. J.Pharmacol.Exp.Ther. 304 729 PMID: 12538828

Koukourakis et al (2016) Normal tissue radioprotection by AmiF. via Warburg-type effects. Sci.Rep. 6 PMID: 27507219

View Related Products by Target

Keywords: Amifostine, Amifostine supplier, amifostine, cytoprotectant, WR, 2721, protects, radiotherapy, chemotherapy, 112901-68-5, Biochemicals, and, Molecular, Biology, 6655, Tocris Bioscience

Citations for Amifostine

Citations are publications that use Tocris products.

Currently there are no citations for Amifostine.

Reviews for Amifostine

There are currently no reviews for this product. Be the first to review Amifostine and earn rewards!

Have you used Amifostine?

Submit a review and receive an Amazon gift card.

$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image

$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review