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Submit ReviewAmifostine
Discontinued Product
6655 has been discontinued.
View all Biochemicals and Molecular Biology products.
Description: Cytoprotectant
Chemical Name: 2-[(3-Aminopropyl)amino]ethanethiol dihydrogen phosphate
Biological Activity for Amifostine
Amifostine is a cytoprotectant against chemotherapy and radiotherapy. Reduces mitochondrial pyruvate use in hepatocytes but not hepatoma cells in vitro. Also inhibits angiogenesis.
Active metabolite is also available, WR 1065 (Cat. No. 3356)
Technical Data for Amifostine
| M. Wt | 214.22 |
| Formula | C5H15N2O3PS |
| Storage | Store at +4°C |
| CAS Number | 20537-88-6 |
| PubChem ID | 2141 |
| InChI Key | JKOQGQFVAUAYPM-UHFFFAOYSA-N |
| Smiles | NCCCNCCSP(O)(O)=O |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Product Datasheets for Amifostine
References for Amifostine
References are publications that support the biological activity of the product.
Giannopoulou et al (2003) AmiF. inhibits angiogenesis in vivo. J.Pharmacol.Exp.Ther. 304 729 PMID: 12538828
Koukourakis et al (2016) Normal tissue radioprotection by AmiF. via Warburg-type effects. Sci.Rep. 6 PMID: 27507219
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Keywords: Amifostine, Amifostine supplier, amifostine, cytoprotectant, WR, 2721, protects, radiotherapy, chemotherapy, 112901-68-5, Biochemicals, and, Molecular, Biology, 6655, Tocris Bioscience
Citations for Amifostine
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