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AKTide-2T

Cat. No. 2422 Submit a Review Datasheet / COA / SDS
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Cat.No. 2422 - AKTide-2T | Ala-Arg-Lys-Arg-Glu-Arg-Thr-Tyr-Ser-Phe-Gly-His-His-Ala | CAS No. 324029-01-8
Description: Akt/PKB substrate (synthetic)
Datasheet
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Biological Activity Technical Data Solubility Calculators Datasheets References

Biological Activity

Peptide substrate for Akt/PKB. Acts as an inhibitor and mimics the optimal phosphorylation sequence of Akt.

Technical Data

M. Wt 1715.89
Formula C74H114N28O20
Sequence ARKRERTYSFGHHA
Storage Desiccate at -20°C
CAS Number 324029-01-8
PubChem ID 90488759
InChI Key HSEMWALZGKQWLK-SWWIKBNJSA-N
Smiles [H]N[C@@H](C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC1=CC=C(O)C=C1)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)NCC(=O)N[C@@H](CC1=CNC=N1)C(=O)N[C@@H](CC1=CNC=N1)C(=O)N[C@@H](C)C(O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility Data

Solubility Soluble to 1 mg/ml in water

References

References are publications that support the biological activity of the product.

Obata et al (2000) Peptide and protein library screening defines optimal substrate motifs for AKT/PKB. J.Biol.Chem. 275 36108 PMID: 10945990

Rane et al (2003) Heat shock protein 27 controls apoptosis by regulating Akt activation. J.Biol.Chem. 278 27828 PMID: 12740362

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Keywords: AKTide-2T, AKTide-2T supplier, Akt, PKB, synthetic, Protein, Kinases, B, Enzyme, Substrates, activators, /, Activators, (Protein, Kinase, B), B/Akt, 2422, Tocris Bioscience

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