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Submit ReviewPeptide substrate for Akt/PKB. Acts as an inhibitor and mimics the optimal phosphorylation sequence of Akt.
M. Wt | 1715.89 |
Formula | C74H114N28O20 |
Sequence | ARKRERTYSFGHHA |
Storage | Desiccate at -20°C |
CAS Number | 324029-01-8 |
PubChem ID | 90488759 |
InChI Key | HSEMWALZGKQWLK-SWWIKBNJSA-N |
Smiles | [H]N[C@@H](C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC1=CC=C(O)C=C1)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)NCC(=O)N[C@@H](CC1=CNC=N1)C(=O)N[C@@H](CC1=CNC=N1)C(=O)N[C@@H](C)C(O)=O |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Solubility | Soluble to 1 mg/ml in water |
References are publications that support the biological activity of the product.
Obata et al (2000) Peptide and protein library screening defines optimal substrate motifs for AKT/PKB. J.Biol.Chem. 275 36108 PMID: 10945990
Rane et al (2003) Heat shock protein 27 controls apoptosis by regulating Akt activation. J.Biol.Chem. 278 27828 PMID: 12740362
If you know of a relevant reference for AKTide-2T, please let us know.
Keywords: AKTide-2T, AKTide-2T supplier, Akt, PKB, synthetic, Protein, Kinases, B, Enzyme, Substrates, activators, /, Activators, (Protein, Kinase, B), B/Akt, 2422, Tocris Bioscience
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