Akt/SKG Substrate Peptide
Biological Activity
Synthetic peptide suitable as a substrate for Akt/PKB. Unlike other substrates, it is not phosphorylated by p70 S6 kinase or MAP kinase activated protein kinase-1.
Technical Data
| M. Wt | 817.95 |
| Formula | C36H59N13O9 |
| Sequence | RPRAATF |
| Storage | Desiccate at -20°C |
| CAS Number | 276680-69-4 |
| PubChem ID | 10440446 |
| InChI Key | XXOREQHVEARXEP-WDKSWFFASA-N |
| Smiles | [H]N[C@@H](CCCNC(N)=N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC1=CC=CC=C1)C(O)=O |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Solubility Data
| Solubility | Soluble to 1 mg/ml in water |
Preparing Stock Solutions
The following data is based on the product molecular weight 817.95. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.22 mL | 6.11 mL | 12.23 mL |
| 5 mM | 0.24 mL | 1.22 mL | 2.45 mL |
| 10 mM | 0.12 mL | 0.61 mL | 1.22 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.24 mL |
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References
References are publications that support the biological activity of the product.
Alessi et al (1996) Molecular basis for the substrate specificity of protein kinase B; comparison with MAPKAP kinase-1 and p70 S6 kinase. FEBS Lett. 399 333 PMID: 8985174
Cutillas et al (2006) Ultrasensitive and absolute quantification of the phosphoinositide 3-kinase / Akt signal transduction pathway by mass spectrometry. Proc.Natl.Acad.Sci.U.S.A. 103 8959 PMID: 16751276
If you know of a relevant reference for Akt/SKG Substrate Peptide, please let us know.
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Keywords: Akt/SKG Substrate Peptide, Akt/SKG Substrate Peptide supplier, Akt, PKB, synthetic, Protein, Kinase, B, Kinases, Enzyme, Substrates, Activators, /, (Protein, B), B/Akt, 1353, Tocris Bioscience
Citations for Akt/SKG Substrate Peptide
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