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Akt/SKG Substrate Peptide

Cat. No. 1353 COA / Product Datasheet SDS
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Cat.No. 1353 - Akt/SKG Substrate Peptide | Arg-Pro-Arg-Ala-Ala-Thr-Phe | CAS No. 276680-69-4
Description: Akt/PKB substrate (synthetic)
Datasheet
Citations
Literature
Biological Activity Technical Data Solubility Calculators Datasheets References

Biological Activity

Synthetic peptide suitable as a substrate for Akt/PKB. Unlike other substrates, it is not phosphorylated by p70 S6 kinase or MAP kinase activated protein kinase-1.

Technical Data

M. Wt 817.95
Formula C36H59N13O9
Sequence RPRAATF
Storage Desiccate at -20°C
CAS Number 276680-69-4
PubChem ID 10440446
InChI Key XXOREQHVEARXEP-WDKSWFFASA-N
Smiles [H]N[C@@H](CCCNC(N)=N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC1=CC=CC=C1)C(O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Solubility Data

SolubilitySoluble to 1 mg/ml in water

Preparing Stock Solutions

The following data is based on the product molecular weight 817.95. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.22 mL 6.11 mL 12.23 mL
5 mM 0.24 mL 1.22 mL 2.45 mL
10 mM 0.12 mL 0.61 mL 1.22 mL
50 mM 0.02 mL 0.12 mL 0.24 mL

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Product Datasheets

Certificate of Analysis / Product Datasheet
Safety Datasheet

References

References are publications that support the products' biological activity.

Alessi et al (1996) Molecular basis for the substrate specificity of protein kinase B; comparison with MAPKAP kinase-1 and p70 S6 kinase. FEBS Lett. 399 333 PMID: 8985174

Cutillas et al (2006) Ultrasensitive and absolute quantification of the phosphoinositide 3-kinase / Akt signal transduction pathway by mass spectrometry. Proc.Natl.Acad.Sci.U.S.A. 103 8959 PMID: 16751276

If you know of a relevant reference for Akt/SKG Substrate Peptide, please let us know.

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Citations for Akt/SKG Substrate Peptide

Citations are publications that use Tocris products.

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Pathways for Akt/SKG Substrate Peptide

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