Raf Kinase Inhibitors

Cat. No. Product Name / Activity
4836 AZ 628
Potent Raf kinase inhibitor
7223 Dabrafenib mesylate
Potent and selective B-Raf, CDK16 and NEK9 inhibitor; anticancer; also targets human proteins in the SARS-CoV-2 interactome
4453 GDC 0879
Potent B-Raf inhibitor
1381 GW 5074
Potent, selective c-Raf1 kinase inhibitor
5260 KG 5
PDGFRβ, B-Raf, c-Raf, FLT3 and KIT inhibitor
2650 SB 590885
Potent B-Raf inhibitor
6814 Sorafenib
Potent Raf-1 inhibitor; also inhibits VEGFR-2, VEGFR-3, PDGFR-β, Flt-3 and cKIT
7309 Vemurafenib
Potent BRAF and CRAF inhibitor