Alcohol Dehydrogenases

Mammalian alcohol dehydrogenases are a family of enzymes which catalyze the oxidation of alcohols into aldehyde or ketones, with the aid of a co-enzyme, NAD+. In humans, there are five classes (I-V) of alcohol dehydrogenases, encoded by at least seven different genes.

Products
Background
Literature
Gene Data

Inhibitors

Cat No Product Name / Activity
3341 JK 184
Alcohol dehydrogenase 7 inhibitor; inhibits downstream Hh signaling pathway

Mammalian alcohol dehydrogenases are a family of enzymes which catalyze the oxidation of alcohols into aldehyde or ketones, with the aid of a co-enzyme, NAD+. Members of this family also metabolize retinol and hydroxysteroids. In humans, there are five classes (I-V) of alcohol dehydrogenases, encoded by at least seven different genes. The primary hepatic enzyme is alcohol dehydrogenase 1, a class I enzyme, which has A, B and C subunits (encoded by the ADH1A, ADH1B and ADH1C genes respectively), and catalyzes the conversion of ethanol to acetaldehyde.

Literature for Alcohol Dehydrogenases

Tocris offers the following scientific literature for Alcohol Dehydrogenases to showcase our products. We invite you to request* or download your copy today!

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New Product Guide (Spring/Summer 2018)

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Alcohol Dehydrogenase Gene Data

Gene Species Gene Symbol Gene Accession No. Protein Accession No.
ADH1A Human ADH1A NM_000667 M12963
Mouse Adh1 NM_007409 P00329
Rat Adh1 NM_019286 P06757
ADH1B Human ADH1B NM_000668 AF153821
ADH1C Human ADH1C NM_000669 M12272
ADH4 Human ADH4 NM_000670 M15943
Mouse Adh4 NM_011996 Q496S1
Rat Adh4 NM_017270 Q64563
ADH5 Human ADH5 NM_000671 M29872
Mouse Adh5 NM_007410 Q6P513
Rat Adh5 NM_001126120 P12711
ADH6 Human ADH6 NM_000672 AK092768
ADH7 Human ADH7 NM_000673 X76342
Mouse Adh7 NM_009626 Q64437
Rat Adh7 NM_134329 P41682