Dehydrogenases

Dehydrogenases are enzymes that catalyze reduction reactions through the transfer of hydrogen ions (protons) from the substrate to an acceptor or co-enzyme. Co-enzymes are small organic molecules involved in enzyme catalysis, such as nicotinamide adenine dinucleotide (NAD+ or NADH), nicotinamide adenine dinucleotide phosphate (NADP+ or NADPH), flavin adenine dinucleotide (FAD) and flavin mononucleotide (FMN).

Targets

Literature

Enzyme Data

Dehydrogenase Target Files

• 11β-Hydroxysteroid Dehydrogenase
• Alcohol Dehydrogenases
• Aldehyde Dehydrogenases

• Isocitrate Dehydrogenase 1 (IDH1)
• Lactate Dehydrogenase A

Related Targets

• Other Dehydrogenases

Literature for Dehydrogenases

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Dehydrogenase Gene Data

Gene	Species	Gene Symbol	Gene Accession No.	Protein Accession No.
11-HSD	Human	HSD11B1	NM_005525	P28845
	Mouse	Hsd11b1	NM_008288	P50172
	Rat	Hsd11b1	NM_017080	Q6TUH9
DHODH	Human	DHODH	NM_001361	Q02127
	Mouse	Dhodh	NM_020046	O35435
	Rat	Dhodh	NM_001008553	Q63707
IMP1	Human	IMPDH1	NM_000883	P20839
	Mouse	Impdh1	NM_011829	P50096
	Rat	Impdh1	NM_001108619	XP_342651
IMP2	Human	IMPDH2	NM_000884	P12268
	Mouse	Impdh2	NM_011830	P24547
	Rat	Impdh2	NM_199099	Q6P9U9
PDHα1	Human	PDHA1	NM_000284	P08559
	Mouse	Pdha1	NM_008810	P35486
	Rat	Pdha1	NM_001004072	P26284
PDHα2	Human	PDHA2	NM_005390	P29803
	Mouse	Pdha2	NM_008811	P35487
	Rat	Pdha2	NM_053994	Q06437
PDHβ	Human	PDHB	NM_000925	P11177
	Mouse	Pdhb	NM_024221	Q9D051
	Rat	Pdhb	NM_001007620	P49432