Cat. No. 5411
Chemical Name: 6-Amino-4-(2,5-dimethoxyphenyl)-1,4
Biological ActivityRalA and RalB GTPase inhibitor (EC50 ~3.5 μM). Inhibits the binding of Ral to RaLBP1. Exhibits no detectable inhibition of Ras or RhoA activity. Suppresses growth of xenograft tumors in mice. Cell permeable.
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All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Datasheet
Yan et al (2014) Discovery and characterization of small molecules that target the GTPase Ral. Nature 515 443. PMID: 25219851.
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Keywords: RBC8, supplier, RalA, RalB, ras, like, GTPase, inhibitors, inhibits, antitumour, antitumor, Tocris Bioscience, GTPase Inhibitor products