Cat. No. 5411
Chemical Name: 6-Amino-4-(2,5-dimethoxyphenyl)-1,4
Biological ActivityRalA and RalB GTPase inhibitor (EC50 ~3.5 μM). Inhibits the binding of Ral to RaLBP1. Exhibits no detectable inhibition of Ras or RhoA activity. Suppresses growth of xenograft tumors in mice. Cell permeable.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Data Sheet
Yan et al (2014) Discovery and characterization of small molecules that target the GTPase Ral. Nature 515 443. PMID: 25219851.
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Keywords: RBC8, supplier, RalA, RalB, ras, like, GTPase, inhibitors, inhibits, antitumour, antitumor, Tocris Bioscience, GTPase Inhibitor products
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