6-Mercaptopurine

Cat. No. 4103

6-Mercaptopurine C5H4N4S [50-44-2]

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Chemical Name: Purine-6(1H)-thione

Biological Activity

Inhibitor of de novo purine synthesis through interference with DNA and RNA synthesis. Immunosuppressive and antileukemic drug; reduces the anticoagulation elicited by warfarin. Active metabolite of azathioprine (Cat. No. 4099).

Technical Data

M.Wt:
152.18
Formula:
C5H4N4S
Solubility:
Soluble to 100 mM in DMSO and to 100 mM in 1eq. NaOH
Purity:
>99 %
Storage:
Store at RT
CAS No:
50-44-2

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Product Datasheet / Safety Datasheet

References are publications that support the products' biological activity.

Sahasranaman et al (2008) Clinical pharmacology and pharmacogenetics of thiopurines. Eur.J.Clin.Pharmacol. 64 753. PMID: 18506437.

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Keywords: 6-Mercaptopurine, supplier, 6-Mercaptopurine, thiopurine, immunosuppressant, drug, 6-MP, purine, analog, chemotherapeutics, Tocris Bioscience, DNA, RNA and Protein Synthesis Inhibitor products

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