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Purine analog. Blocks DNA replication and the de novo pathway of purine synthesis. Immunosuppressive and anti-inflammatory drug; induces apoptosis in human T-lymphocytes. Prodrug of 6-mercaptopurine (Cat. No. 4103).
|Storage||Store at -20°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
|Solvent||Max Conc. mg/mL||Max Conc. mM|
Preparing Stock Solutions
The following data is based on the product molecular weight 277.26. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||3.61 mL||18.03 mL||36.07 mL|
|5 mM||0.72 mL||3.61 mL||7.21 mL|
|10 mM||0.36 mL||1.8 mL||3.61 mL|
|50 mM||0.07 mL||0.36 mL||0.72 mL|
References are publications that support the biological activity of the product.
Maltzman and Koretzky (2003) Azathioprine: old drug, new actions. J.Clin.Invest. 111 1122 PMID: 12697731
If you know of a relevant reference for Azathioprine, please let us know.
Keywords: Azathioprine, Azathioprine supplier, Azathioprine, immunosuppressant, inhibits, DNA, synthesis, inhibitors, lymphocyte, purine, analog, DNA,, RNA, and, Protein, Synthesis, Immunosuppressants, 4099, Tocris Bioscience
Citations for Azathioprine
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Reviews for Azathioprine
Average Rating: 5 (Based on 1 Review.)
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Azathioprine was used at a 20 uM concentration for in vitro culture with SK-MEL-28 and cell viability was monitored over time with live imaging. Arrow indicates when compound was added to media.
Literature in this Area
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