TCS 2210

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Cat.No. 3877 - TCS 2210 | C18H17N3O3 | CAS No. 1201916-31-5
Description: Inducer of neuronal differentiation in MSCs
Chemical Name: 1,2-Dihydro-N-hydroxy-2-oxo-3-(3-phenylpropyl)-6-quinoxalinecarboxamide
Datasheet
Citations (1)
Reviews
Literature (4)

Biological Activity

Inducer of neuronal differentiation in mesenchymal stem cells (MSCs) with specific phenotype change. Increases expression of neuronal markers β-III tubulin and NSE without cytotoxicity.

Compound Libraries

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Technical Data

M. Wt 323.35
Formula C18H17N3O3
Storage Store at -20°C
CAS Number 1201916-31-5
PubChem ID 44607172
InChI Key ZOFZKGFBKISZRI-UHFFFAOYSA-N
Smiles O=C(NO)C3=CC1=C(C=C3)NC(C(CCCC2=CC=CC=C2)=N1)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility Data

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 16.17 50

Preparing Stock Solutions

The following data is based on the product molecular weight 323.35. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.5 mM 6.19 mL 30.93 mL 61.85 mL
2.5 mM 1.24 mL 6.19 mL 12.37 mL
5 mM 0.62 mL 3.09 mL 6.19 mL
25 mM 0.12 mL 0.62 mL 1.24 mL

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References

References are publications that support the biological activity of the product.

Kim et al (2009) Discovery of a new and efficient small molecule for neuronal differentiation from mesenchymal stem cell. J.Med.Chem. 52 7931 PMID: 20014867


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Keywords: TCS 2210, TCS 2210 supplier, TCS2210, neuronal, inducers, differentiation, mesenchymal, stem, cells, MSC, induces, Mesenchymal, Stem, Cells, Neural, 3877, Tocris Bioscience

1 Citation for TCS 2210

Citations are publications that use Tocris products. Selected citations for TCS 2210 include:

Moshfegh et al (2016) A gonogenic stimulated transition of mouse embryonic stem cells with enhanced control of diverse differentiation pathways. PLoS One 6 25104 PMID: 27157261


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Literature in this Area

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