Sulforhodamine 101
Biological Activity
Fluorescent dye (excitation maximum ~ 586 nm; emission maximum ~ 606). Selective astrocyte marker. Sulforhodamine 101 acid chloride (Cat. No. 5442) also available.
Technical Data
| M. Wt | 606.71 |
| Formula | C31H30N2O7S2 |
| Storage | Store at +4°C |
| Purity | ≥95% (HPLC) |
| CAS Number | 60311-02-6 |
| PubChem ID | 122180 |
| InChI Key | COIVODZMVVUETJ-UHFFFAOYSA-N |
| Smiles | O=S(C(C=C8)=CC(S(=O)([O-])=O)=C8C(C(C=C7C6=C5CCCN6CCC7)=C5O4)=C(C4=C2CCC3)C=C1C2=[N+]3CCC1)(O)=O |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Solubility Data
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 30.34 | 50 | |
| water | 30.34 | 50 |
Preparing Stock Solutions
The following data is based on the product molecular weight 606.71. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.65 mL | 8.24 mL | 16.48 mL |
| 5 mM | 0.33 mL | 1.65 mL | 3.3 mL |
| 10 mM | 0.16 mL | 0.82 mL | 1.65 mL |
| 50 mM | 0.03 mL | 0.16 mL | 0.33 mL |
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Product Datasheets
References
References are publications that support the biological activity of the product.
Nimmerjahn et al (2004) Sulforhodamine 101 as a specific marker of astroglia in the neocortex in vivo. Nat.Methods 1 31 PMID: 15782150
roth et al (2014) Transcranial amelioration of inflammation and cell death after brain injury. Nature 505 223 PMID: 24317693
If you know of a relevant reference for Sulforhodamine 101, please let us know.
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