Sulforhodamine 101

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Cat.No. 5146 - Sulforhodamine 101 | C31H30N2O7S2 | CAS No. 60311-02-6
Description: Red fluorescent dye; selective astrocyte marker
Chemical Name: 9-(2,4-Disulfophenyl)-2,3,6,7,12,13,16,17-octahydro-1H,5H,11H,15H-xantheno[2,3,4-ij:5,6,7-i'j']diquinolizin-18-ium inner salt
Purity: ≥95% (HPLC)
Literature (1)

Biological Activity

Fluorescent dye (excitation maximum ~ 586 nm; emission maximum ~ 606). Selective astrocyte marker. Sulforhodamine 101 acid chloride (Cat. No. 5442) also available.

Technical Data

M. Wt 606.71
Formula C31H30N2O7S2
Storage Store at +4°C
Purity ≥95% (HPLC)
CAS Number 60311-02-6
PubChem ID 122180
Smiles O=S(C(C=C8)=CC(S(=O)([O-])=O)=C8C(C(C=C7C6=C5CCCN6CCC7)=C5O4)=C(C4=C2CCC3)C=C1C2=[N+]3CCC1)(O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility Data

Solvent Max Conc. mg/mL Max Conc. mM
ethanol 12.13 20
water 30.34 50

Preparing Stock Solutions

The following data is based on the product molecular weight 606.71. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.5 mM 3.3 mL 16.48 mL 32.96 mL
2.5 mM 0.66 mL 3.3 mL 6.59 mL
5 mM 0.33 mL 1.65 mL 3.3 mL
25 mM 0.07 mL 0.33 mL 0.66 mL

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Product Datasheets

Certificate of Analysis / Product Datasheet
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References are publications that support the biological activity of the product.

Nimmerjahn et al (2004) Sulforhodamine 101 as a specific marker of astroglia in the neocortex in vivo. Nat.Methods 1 31 PMID: 15782150

roth et al (2014) Transcranial amelioration of inflammation and cell death after brain injury. Nature 505 223 PMID: 24317693

If you know of a relevant reference for Sulforhodamine 101, please let us know.

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Literature in this Area

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