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Discontinued ProductSTK16-IN-1 (Cat. No. 6036) has been withdrawn from sale for commercial reasons.
Biological Activity for STK16-IN-1
STK16-IN-1 is a serine/threonine protein kinase 16 (STK16) inhibitor (IC50 = 295 nM). Reduces cell number and increases accumulation of binucleated MCF-1 cells. Enhances cell apoptosis in combination with chemotherapeutics. Also inhibits PI 3-Kδ and PI-3-Kγ kinases (IC50 values are 856 and 867 nM, respectively) and mTOR kinase (IC50= 5.56 μM).
Sold under license from Whitehead Institute for Biomedical Research.
Technical Data for STK16-IN-1
|Storage||Store at +4°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
References for STK16-IN-1
References are publications that support the biological activity of the product.
Liu et al (2016) Discovery of a highly selective STK16 kinase inhibitor ACS.Chem.Biol. 11 1537 PMID: 27082499
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Keywords: STK16-IN-1, STK16-IN-1 supplier, Serine/Threonine, kinase, Ser/Thr, STK16, STK16-IN-1, inhibitors, inhibits, binucleated, cells, apoptosis, chemotherapy, chemotherapeutics, PI, 3K, mTOR, Other, Kinases, 3-Kinase, 6036, Tocris Bioscience
Citations for STK16-IN-1
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Currently there are no citations for STK16-IN-1.
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