SNC 121

Discontinued Product

Unfortunately SNC 121 (Cat. No. 1008) has been withdrawn from sale for commercial reasons.
Cat.No. 1008 - SNC 121 | C28H41N3O2 | CAS No. 159860-31-8
Description: Highly selective non-peptide δ agonist. Analog of SNC 80 (Cat. No. 0764)
Chemical Name: 4-[(αR)-α-((2S,5R)-4-Propyl-2,5-dimethyl-1-piperazinyl)-3-methoxybenzyl]-N,N-diethylbenzamide
Purity: ≥99% (HPLC)
Datasheet
Citations
Reviews
Literature

Biological Activity

Saturated analog of the potent and selective δ opioid receptor agonist SNC 80 (Cat. No. 0764), with a similar binding profile to the parent compound.

Technical Data

M. Wt 451.65
Formula C28H41N3O2
Storage Store at RT
Purity ≥99% (HPLC)
CAS Number 159860-31-8
Smiles O=C(N(CC)CC)C1=CC=C([C@@](N3C[C@@H](C)N(CCC)C[C@@H]3C)([H])C2=CC(OC)=CC=C2)C=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Preparing Stock Solutions

The following data is based on the product molecular weight 451.65. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.21 mL 11.07 mL 22.14 mL
5 mM 0.44 mL 2.21 mL 4.43 mL
10 mM 0.22 mL 1.11 mL 2.21 mL
50 mM 0.04 mL 0.22 mL 0.44 mL

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.
=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Dilution Calculator

Calculate the dilution required to prepare a stock solution.
x
=
x

Product Datasheets

Certificate of Analysis / Product Datasheet
Select another batch:
Safety Datasheet

References

References are publications that support the products' biological activity.

Knapp et al (1996) Structure-activity relationships for SNC80 and related compounds at cloned human delta and mu opioid receptors. J.Pharmacol.Exp.Ther. 277 1284 PMID: 8667189

Ni et al (1995) Opioid peptide receptor studies 2. [3H]SNC-121, a novel, selective and high affinity ligand for opioid delta receptors. Analgesia 1 185 PMID:

View Related Products by Target

View Related Products by Product Action

View all δ Opioid Receptor Agonists

Keywords: SNC 121, supplier, Potent, δ-opioid, delta-opioid, DOP, Receptors, OP1, SNC121, Delta, Opioid, Receptors, Delta, Opioid, Receptors, Tocris Bioscience

Citations for SNC 121

Citations are publications that use Tocris products.

Currently there are no citations for SNC 121.

Reviews for SNC 121

There are currently no reviews for this product. Be the first to review SNC 121 and earn rewards!

Have you used SNC 121?

Submit a review and receive an Amazon gift card.

$10US/$10CAN/€7/£6 gift card for a review without an image

$25US/$25CAN/€18/£15 gift card for a review with an image

*Offer only valid in the USA / Canada, UK and Europe

Submit a Review

Literature in this Area

GPCR

GPCR Product Listing

A collection of over 450 products for G protein-coupled receptors, the listing includes research tools for the study of:

  • Rhodopsin-like Receptors
  • Secretin-like Receptors
  • Glutamate Receptors
  • Frizzled Receptors
  • GPCR Signaling
Pain

Pain Research Product Guide

A collection of over 250 products for pain research, the guide includes research tools for the study of:

  • Nociception
  • Ion Channels
  • G-Protein-Coupled Receptors
  • Intracellular Signaling
Peptides Involved in Appetite Modulation

Peptides Involved in Appetite Modulation Scientific Review

Written by Sonia Tucci, Lynsay Kobelis and Tim Kirkham, this review provides a synopsis of the increasing number of peptides that have been implicated in appetite regulation and energy homeostasis; putative roles of the major peptides are outlined and compounds available from Tocris are listed.

Addiction

Addiction Poster

The key feature of drug addiction is the inability to stop using a drug despite clear evidence of harm. This poster describes the brain circuits associated with addiction, and provides an overview of the main classes of addictive drugs and the neurotransmitter systems that they target.

Pain

Pain Poster

Peripheral sensitization is the reduction in the threshold of excitability of sensory neurons that results in an augmented response to a given external stimulus. This poster outlines the excitatory and inhibitory signaling pathways involved in modulation of peripheral sensitization. The role of ion channels, GPCRs, neurotrophins, and cytokines in sensory neurons are also described.